Breast cancer is a common cancer affecting a large number of patients. Notably, 5–10% of
all breast cancer patients are genetically predisposed to cancers. Although the most …

Introduction Germline mutation in CDH1 (E-cadherin) tumor suppressor gene is associated
with hereditary diffuse gastric cancer (HDGC) and lobular breast cancers (LBC). E-Cadherin …

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The epithelial–mesenchymal transition (EMT) is thought to be at the root of invasive and
metastatic cancer cell spreading. E-cadherin is an important player in this process, which …

Hereditary diffuse gastric cancer (HDGC) is a dominantly inherited cancer syndrome
characterized by a high incidence of diffuse gastric cancer (DGC) and lobular breast cancer …

Simple Summary The effectiveness and safety of the anti-cancer agent doxorubicin
(anthracycline group medicine) depend on the metabolism and retention of the drug in the …

The prevalence of gastric cancer (GC) differs among regions worldwide, with the highest
occurrence in east Asia. Thus, its etiology, with respect to ethnic background, environmental …

Background LncRNA was known to be closely associated with the progression of human
tumors. The role of lncRNA LIFR-AS1 in the pathogenesis and progression of gastric tumor …

PURPOSE To determine the contribution of germline pathogenic variants (PVs) in hereditary
cancer testing panel genes to invasive lobular carcinoma (ILC) of the breast. MATERIALS …

Hereditary diffuse gastric cancer is an autosomal dominant syndrome characterized by a
high prevalence of diffuse gastric cancer and lobular breast cancer. It is caused by …