Wound healing is an intricate process that requires complex coordination between many cell
types and an appropriate extracellular microenvironment. Chronic wounds often suffer from …

Diabetic foot ulcers (DFUs) are a serious complication from diabetes mellitus, with a huge
economic, social and psychological impact on the patients' life. One of the main reasons why …

Since the introduction of antibiotics into human medicine in the 1940's, antibiotic resistance
has emerged at an alarming rate and is now a major threat to public health. This problem is …

Diabetic foot infection is the leading cause of non-traumatic lower limb amputations
worldwide. In addition, diabetes mellitus and sequela of the disease are increasing in …

Diabetic foot ulcers (DFUs) and diabetic foot infections (DFIs) are associated with reduced
patient quality of life, lower-extremity amputation, hospitalization, and high morbidity and …

In addition to being the prime factor associated with amputation, diabetic foot infections
(DFIs) are associated with major morbidity, increasing mortality, and reduced quality of life …

This compendium is a follow-up to the 2018 American Diabetes Association compendium
Diagnosis and Management of Diabetic Foot Complications. Whereas the first compendium …

The number of people in the world with diabetes has nearly quadrupled in the past 40 years.
Current data show that 25% of these diabetics will develop a foot ulcer in their lifetime and …

Diabetic foot infection (DFI) management requires complex multidisciplinary care pathways
with off-loading, debridement and targeted antibiotic treatment central to positive clinical …

Background Healthcare events related to diabetic foot disease carry a burden of morbidity,
mortality and economic cost. Prompt identification of clinical infection with appropriate tissue …