Phospholipase A2 myotoxins from Bothrops snake venoms
JM Gutiérrez, B Lomonte - Toxicon, 1995 - Elsevier
Several myotoxins have been isolated from Bothrops snake venoms during the last 10
years. All of them are group II basic phospholipases A2, although some lack enzymatic …
years. All of them are group II basic phospholipases A2, although some lack enzymatic …
[图书][B] Handbook of venoms and toxins of reptiles
SP Mackessy - 2016 - taylorfrancis.com
The Handbook of Venoms and Toxins of Reptiles offers" one-stop shopping" to all biologists,
biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed …
biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed …
An overview of lysine-49 phospholipase A2 myotoxins from crotalid snake venoms and their structural determinants of myotoxic action
B Lomonte, Y Angulo, L Calderón - Toxicon, 2003 - Elsevier
In 1984, the first venom phospholipase A2 (PLA2) with a lysine substituting for the highly
conserved aspartate 49 was discovered, in the North American crotalid snake Agkistrodon p …
conserved aspartate 49 was discovered, in the North American crotalid snake Agkistrodon p …
Snake venom Lys49 myotoxins: from phospholipases A2 to non-enzymatic membrane disruptors
B Lomonte, J Rangel - Toxicon, 2012 - Elsevier
Snake venoms often contain toxins that cause a rapid necrosis of skeletal muscle fibers,
referred to as myotoxins. The most common among them are phospholipases A2 (PLA2s) …
referred to as myotoxins. The most common among them are phospholipases A2 (PLA2s) …
Lys49 myotoxins, secreted phospholipase A2-like proteins of viperid venoms: A comprehensive review
B Lomonte - Toxicon, 2023 - Elsevier
Muscle necrosis is a potential clinical complication of snakebite envenomings, which in
severe cases can lead to functional or physical sequelae such as disability or amputation …
severe cases can lead to functional or physical sequelae such as disability or amputation …
[HTML][HTML] Cloning and expression of a membrane receptor for secretory phospholipases A2.
G Lambeau, P Ancian, J Barhanin… - Journal of Biological …, 1994 - Elsevier
Snake venom and mammalian secretory phospholipases A2 are structurally related
enzymes that have been associated with several toxic (neurotoxicity, myotoxicity, etc.) …
enzymes that have been associated with several toxic (neurotoxicity, myotoxicity, etc.) …
Structures of Free and Inhibited Human Secretory Phospholipase A2 from Inflammatory Exudate
DL Scott, SP White, JL Browning, JJ Rosa, MH Gelb… - Science, 1991 - science.org
Phospholipase A2 (PLA2) participates in a wide range of cellular processes including
inflammation and transmembrane signaling. A human nonpancreatic secretory PLA2 (hnps …
inflammation and transmembrane signaling. A human nonpancreatic secretory PLA2 (hnps …
Neutralizing interaction between heparins and myotoxin II, a lysine 49 phospholipase A2 from Bothrops asper snake venom. Identification of a heparin-binding and …
Heparin binds to phospholipase A2 myotoxins from Bothrops asper snake venom, inhibiting
their toxic activities. This interaction was investigated using purified myotoxin II, a Lys-49 …
their toxic activities. This interaction was investigated using purified myotoxin II, a Lys-49 …
Accuracy and precision in protein structure analysis: restrained least-squares refinement of the structure of poplar plastocyanin at 1.33 Å resolution
JM Guss, HD Bartunik, HC Freeman - … Crystallographica Section B …, 1992 - journals.iucr.org
The structure of the electron-transfer protein, plas-tocyanin (99 amino acids, one Cu atom,
10 500 Da) from poplar leaves, has been refined at 1.33 A resolu-tion to a residual R= 0.15 …
10 500 Da) from poplar leaves, has been refined at 1.33 A resolu-tion to a residual R= 0.15 …