Abstract Global Developmental Delay/Intellectual disability (ID) is the term used to describe
various disorders caused by abnormal brain development and characterized by impairments …

BLOC-one-related complex (BORC) is a multiprotein complex composed of eight subunits
named BORCS1–8. BORC associates with the cytosolic face of lysosomes, where it …

Secreted proteins fulfill a vast array of functions, including immunity, signaling, and
extracellular matrix remodeling. In the trans-Golgi network, proteins destined for constitutive …

During the past 3000 years, cattle on the Qinghai-Xizang Plateau have developed adaptive
phenotypes under the selective pressure of hypoxia, ultraviolet (UV) radiation, and extreme …

Phosphoinositides help steer membrane trafficking routes within eukaryotic cells. In
polarized exocytosis, which targets vesicular cargo to sites of polarized growth at the plasma …

CLEC16A is a membrane-associated C-type lectin protein that functions as a E3-ubiquitin
ligase. CLEC16A regulates autophagy and mitophagy, and reportedly localizes to late …

Myhre syndrome is a connective tissue disorder characterized by congenital cardiovascular,
craniofacial, respiratory, skeletal, and cutaneous anomalies as well as intellectual disability …

Abstract Eukaryotic Initiation Translation Factor 2A (EIF2A) is considered to be primarily
responsible for the initiation of translation when a cell is subjected to stressful conditions …

To assemble a brain, differentiating neurons must make proper connections and establish
specialized brain compartments. Abnormal levels of cell adhesion molecules disrupt these …

The giant grouper fish (Epinephelus lanceolatus), one of the largest and rarest groupers, is a
fast-growing economic fish. Grouper sperm is often used for cross-breeding with other fish …