Olfaction is a critical sensory modality that allows living things to acquire chemical
information from the external world. The olfactory system processes two major classes of …

The chemical senses (smell and taste) have evolved complex repertoires of chemosensory
receptors—G-protein coupled receptors with a seven-transmembrane domain structure. In …

Deciphering olfactory encoding requires a thorough description of the ligands that activate
each odorant receptor (OR). In mammalian systems, however, ligands are known for fewer …

Understanding differences in the repertoire of orthologous gene pairs is vital for
interpretation of pharmacological and physiological experiments if conclusions are …

In recent years, considerable progress has been achieved in the comprehension of the
profound effects of pheromones on reproductive physiology and behavior. Pheromones …

Essential oils have been used in multiple ways, ie, inhaling, topically applying on the skin,
and drinking. Thus, there are three major routes of intake or application involved: the …

Recently, modern neuroscience has made considerable progress in understanding how the
brain perceives, discriminates, and recognizes odorant molecules. This growing knowledge …

The transcriptional activation of one out of∼ 2800 olfactory receptor (OR) alleles is a poorly
understood process. Here, we identify a plethora of putative OR enhancers and study their in …

Charles Darwin proposed that evolution occurs primarily by natural selection, but this view
has been controversial from the beginning. Two of the major opposing views have been …

The main olfactory epithelium of the mouse is a mosaic of 2000 populations of olfactory
sensory neurons (OSNs). Each population expresses one allele of one of the 1000 intact …