Neurofilaments as biomarkers in neurological disorders
M Khalil, CE Teunissen, M Otto, F Piehl… - Nature Reviews …, 2018 - nature.com
Neuroaxonal damage is the pathological substrate of permanent disability in various
neurological disorders. Reliable quantification and longitudinal follow-up of such damage …
neurological disorders. Reliable quantification and longitudinal follow-up of such damage …
Blood neurofilament light: a critical review of its application to neurologic disease
Neuronal injury is a universal event that occurs in disease processes that affect both the
central and peripheral nervous systems. A blood biomarker linked to neuronal injury would …
central and peripheral nervous systems. A blood biomarker linked to neuronal injury would …
An update on diagnostic and prognostic biomarkers for traumatic brain injury
Introduction: Traumatic brain injury (TBI) is a major worldwide neurological disorder of
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …
Traumatic brain injuries
Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe.
Mild TBI (the least severe form) is synonymous with concussion and is typically caused by …
Mild TBI (the least severe form) is synonymous with concussion and is typically caused by …
The multifaceted role of neurofilament light chain protein in non-primary neurological diseases
The advancing validation and exploitation of CSF and blood neurofilament light chain
protein as a biomarker of neuroaxonal damage has deeply changed the current diagnostic …
protein as a biomarker of neuroaxonal damage has deeply changed the current diagnostic …
Fluid biomarkers for mild traumatic brain injury and related conditions
H Zetterberg, K Blennow - Nature reviews neurology, 2016 - nature.com
Diagnostic and prognostic biomarkers for mild traumatic brain injury (TBI), also known as
concussion, remain a major unmet clinical need. Moderate to severe TBI can be diagnosed …
concussion, remain a major unmet clinical need. Moderate to severe TBI can be diagnosed …
The biological significance and clinical utility of emerging blood biomarkers for traumatic brain injury
Abstract HUIBREGTSE, ME, Bazarian, JJ, Shultz, SR, and Kawata K. The biological
significance and clinical utility of emerging blood biomarkers for traumatic brain injury …
significance and clinical utility of emerging blood biomarkers for traumatic brain injury …
Exosomal neurofilament light: A prognostic biomarker for remote symptoms after mild traumatic brain injury?
Objective To measure exosomal and plasma levels of candidate blood biomarkers in
veterans with history of mild traumatic brain injury (mTBI) and test their relationship with …
veterans with history of mild traumatic brain injury (mTBI) and test their relationship with …
Post-concussion syndrome and chronic traumatic encephalopathy: narrative review on the neuropathology, neuroimaging and fluid biomarkers
I Mavroudis, D Kazis, R Chowdhury, F Petridis, V Costa… - Diagnostics, 2022 - mdpi.com
Traumatic brain injury is a significant public health issue and represents the main contributor
to death and disability globally among all trauma-related injuries. Martial arts practitioners …
to death and disability globally among all trauma-related injuries. Martial arts practitioners …
Acute peri‐operative neurocognitive disorders: a narrative review
Peri‐operative neurocognitive disorders are the most common complication experienced by
older individuals undergoing anaesthesia and surgery. Peri‐operative neurocognitive …
older individuals undergoing anaesthesia and surgery. Peri‐operative neurocognitive …