Fullerenes in biology and medicine

E Castro, AH Garcia, G Zavala… - Journal of Materials …, 2017 - pubs.rsc.org
Fullerenes and related carbon based derivatives have shown a growing relevance in
biology and medicine, mainly due to the unique electronic and structural properties that …

Nanotoxicity: an interplay of oxidative stress, inflammation and cell death

P Khanna, C Ong, BH Bay, GH Baeg - Nanomaterials, 2015 - mdpi.com
Nanoparticles are emerging as a useful tool for a wide variety of biomedical, consumer and
instrumental applications that include drug delivery systems, biosensors and environmental …

Neutrophils and macrophages as targets for development of nanotherapeutics in inflammatory diseases

Y Su, J Gao, P Kaur, Z Wang - Pharmaceutics, 2020 - mdpi.com
Neutrophils and macrophages are major components of innate systems, playing central
roles in inflammation responses to infections and tissue injury. If they are out of control …

Recent insights on indirect mechanisms in developmental toxicity of nanomaterials

BB Dugershaw, L Aengenheister, SSK Hansen… - Particle and Fibre …, 2020 - Springer
Background Epidemiological and animal studies provide compelling indications that
environmental and engineered nanomaterials (NMs) pose a risk for pregnancy, fetal …

Towards understanding mechanisms governing cytotoxicity of metal oxides nanoparticles: Hints from nano-QSAR studies

A Gajewicz, N Schaeublin, B Rasulev, S Hussain… - …, 2015 - Taylor & Francis
The production of nanomaterials increases every year exponentially and therefore the
probability these novel materials that they could cause adverse outcomes for human health …

Nanoparticles induce dermal and intestinal innate immune system responses in zebrafish embryos

NR Brun, BEV Koch, M Varela… - Environmental …, 2018 - pubs.rsc.org
Major molecular mechanisms that underpin the toxicity of nanoparticles (NPs) are the
formation of reactive oxygen species and the induction of inflammation. The latter is …

Molecular and immunological toxic effects of nanoparticles

RK Pandey, VK Prajapati - International journal of biological …, 2018 - Elsevier
Nanoparticles have emerged as a boon for the public health applications such as drug
delivery, diagnostic, and imaging. Biodegradable and non-bio degradable nanoparticles …

Nano-bio interactions: a neutrophil-centric view

S Keshavan, P Calligari, L Stella, L Fusco… - Cell Death & …, 2019 - nature.com
Neutrophils are key components of the innate arm of the immune system and represent the
frontline of host defense against intruding pathogens. However, neutrophils can also cause …

Biomedical nanomaterials for immunological applications: ongoing research and clinical trials

V Lenders, X Koutsoumpou, A Sargsian… - Nanoscale …, 2020 - pubs.rsc.org
Research efforts on nanomaterial-based therapies for the treatment of autoimmune diseases
and cancer have spiked and have made rapid progress over the past years. Nanomedicine …

Biodegradation of carbon nanotubes by macrophages

M Yang, M Zhang - Frontiers in Materials, 2019 - frontiersin.org
Carbon nanotubes (CNTs) are considered to be among the most promising materials of the
twenty first century due to their electronic, optical, mechanical, and thermodynamic …