New diagnostic criteria and better definitions of tumor types aim at improving the
management of brain tumor patients and at better evaluating new treatments in clinical trials …

Simple Summary Adult medulloblastoma is an extremely rare tumor of the central nervous
system. Standard multimodal treatment, comprising maximal safe surgical resection followed …

PURPOSE Infant and young childhood medulloblastoma (iMB) is usually treated without
craniospinal irradiation (CSI) to avoid neurocognitive late effects. Unfortunately, many …

Medulloblastoma is the most common malignant CNS tumor of childhood, affecting~ 350
patients/year in the USA. In 2020, most children are cured of their disease, however …

Posterior fossa tumours (PFTs) in infants are very rare, and information on these tumours is
scarce in the literature. This retrospective study reports their pathological characteristics and …

Medulloblastomas, highly aggressive neoplasms of the central nervous system (CNS) that
present significant heterogeneity in clinical presentation, disease course, and treatment …

Background The prognostic impact of clinical risk factors and DNA methylation patterns in
sonic hedgehog (SHH)-activated early childhood desmoplastic/nodular medulloblastoma …

Background: Periodic updates to the World Health Organization (WHO) classification system
for central nervous system (CNS) tumors reflect advances in the pathological diagnosis …

Background: Central nervous system tumors are the most common solid tumors in
childhood. Treatment paradigms for pediatric central nervous system malignancies depend …

Abstract Background Congenital (< 3 months) and infant (3 to 11 months) brain tumors are
biologically different from tumors in older children, but their epidemiology has not been …