Naringin ameliorates sodium arsenite-induced renal and hepatic toxicity in rats: decisive role of KIM-1, Caspase-3, TGF-β, and TNF-α
Chronic exposure of a naturally occurring metal arsenic leads to renal and hepatic diseases.
Naringin, a flavanone glycoside, possesses anti-inflammatory and anti-oxidant potential …
Naringin, a flavanone glycoside, possesses anti-inflammatory and anti-oxidant potential …
[HTML][HTML] Hesperidin, a plant flavonoid accelerated the cutaneous wound healing in streptozotocin-induced diabetic rats: Role of TGF-ß/Smads and Ang-1/Tie-2 …
Background: Delayed wound healing is a diverse, multifactorial, complex and inter-related
complication of diabetes resulting in significant clinical morbidity. Hesperidin possesses …
complication of diabetes resulting in significant clinical morbidity. Hesperidin possesses …
Wound healing potential of naringin ointment formulation via regulating the expression of inflammatory, apoptotic and growth mediators in experimental rats
AD Kandhare, J Alam, MVK Patil, A Sinha… - Pharmaceutical …, 2016 - Taylor & Francis
Context: Wound healing is a consequence of a complex process involving inflammatory,
proliferative, and remodeling phases. Naringin, a flavanone glycoside, is associated with …
proliferative, and remodeling phases. Naringin, a flavanone glycoside, is associated with …
[HTML][HTML] Naringin ameliorates acetic acid induced colitis through modulation of endogenous oxido-nitrosative balance and DNA damage in rats
VS Kumar, AR Rajmane, M Adil… - Journal of biomedical …, 2014 - ncbi.nlm.nih.gov
The aim of this study was to evaluate the effect of naringin on experimentally induced
inflammatory bowel disease in rats. Naringin (20, 40 and 80 mg/kg) was given orally for 7 …
inflammatory bowel disease in rats. Naringin (20, 40 and 80 mg/kg) was given orally for 7 …
Hepatoprotective effect of withanolide-rich fraction in acetaminophen-intoxicated rat: decisive role of TNF-α, IL-1β, COX-II and iNOS
ST Devkar, AD Kandhare, AA Zanwar… - Pharmaceutical …, 2016 - Taylor & Francis
Context: Overdose of acetaminophen (APAP) is common in humans and is often associated
with hepatic damage. Withania somnifera (L.) Dunal (Solanaceae) shows multiple …
with hepatic damage. Withania somnifera (L.) Dunal (Solanaceae) shows multiple …
Pharmacological evaluation of ethanolic extract of Daucus carota Linn root formulated cream on wound healing using excision and incision wound model
MVK Patil, AD Kandhare, SD Bhise - Asian Pacific Journal of Tropical …, 2012 - Elsevier
Abstract Objective Daucus carota L.(Carrot)(Apiaceae) is used in the traditional medicine for
the treatment of variety of ailments. The aim of present investigation was to formulate and …
the treatment of variety of ailments. The aim of present investigation was to formulate and …
Evaluation of the neuroprotective effect of chrysin via modulation of endogenous biomarkers in a rat model of spinal cord injury
AD Kandhare, V Shivakumar, A Rajmane… - Journal of natural …, 2014 - Springer
The objective of the present investigation was to evaluate the neuroprotective efficacy of
chrysin in an experimental rat model of spinal cord injury (SCI). SCI was induced in male …
chrysin in an experimental rat model of spinal cord injury (SCI). SCI was induced in male …
Ameliorative effects quercetin against impaired motor nerve function, inflammatory mediators and apoptosis in neonatal streptozotocin-induced diabetic neuropathy in …
AD Kandhare, KS Raygude, VS Kumar… - Biomedicine & Aging …, 2012 - Elsevier
In developing as well as developed countries, diabetes mellitus is one of the major
problems. Oxidative stress plays a vital role in generation and maintenance of the diabetic …
problems. Oxidative stress plays a vital role in generation and maintenance of the diabetic …
Anti-inflammatory and antioxidant potential of Guaianolide isolated from Cyathocline purpurea: Role of COX-2 inhibition
UU Tambewagh, AD Kandhare, VS Honmore… - International …, 2017 - Elsevier
Background Inflammation activated by oxidative stress can cause various diseases, such as
asthma, rheumatoid arthritis, cancer, diabetes, etc. Plant constituents with sesquiterpene …
asthma, rheumatoid arthritis, cancer, diabetes, etc. Plant constituents with sesquiterpene …
Omega-3-fatty acid adds to the protective effect of flax lignan concentrate in pressure overload-induced myocardial hypertrophy in rats via modulation of oxidative …
AE Ghule, AD Kandhare, SS Jadhav, AA Zanwar… - International …, 2015 - Elsevier
Objective of the present investigation was to study the effect of the flax lignan concentrate
(FLC) and Omega-3-fatty acid (O-3-FA) on myocardial apoptosis, left ventricular (LV) …
(FLC) and Omega-3-fatty acid (O-3-FA) on myocardial apoptosis, left ventricular (LV) …