Using singlet oxygen to synthesize natural products and drugs

AA Ghogare, A Greer - Chemical reviews, 2016 - ACS Publications
This Review describes singlet oxygen (1O2) in the organic synthesis of targets on possible
1O2 biosynthetic routes. The visible-light sensitized production of 1O2 is not only useful for …

Dearomatization strategies in the synthesis of complex natural products

SP Roche, JA Porco Jr - Angewandte Chemie International …, 2011 - Wiley Online Library
Evolution in the field of the total synthesis of natural products has led to exciting
developments over the last decade. Numerous chemoselective and enantioselective …

Metathesis reactions in total synthesis

KC Nicolaou, PG Bulger… - Angewandte Chemie …, 2005 - Wiley Online Library
With the exception of palladium‐catalyzed cross‐couplings, no other group of reactions has
had such a profound impact on the formation of carbon–carbon bonds and the art of total …

[HTML][HTML] Rearrangements of organic peroxides and related processes

IA Yaremenko, VA Vil, DV Demchuk… - Beilstein journal of …, 2016 - beilstein-journals.org
This review is the first to collate and summarize main data on named and unnamed
rearrangement reactions of peroxides. It should be noted, that in the chemistry of peroxides …

Advances in singlet oxygen chemistry

EL Clennan, A Pace - Tetrahedron, 2005 - Elsevier
Oxygen is ubiquitous. It comprises nearly 50% of the Earth's crust and is an essential
component in metabolic pathways in all higher organisms. 1 It was first identified by Carl …

Using singlet oxygen to synthesize polyoxygenated natural products from furans

T Montagnon, M Tofi… - Accounts of chemical …, 2008 - ACS Publications
Singlet oxygen is a powerful tool in the armament of the synthetic organic chemist and
possibly in that of nature itself. In this Account, we illustrate a small selection of the many …

Desaromatisierungsstrategien in der Synthese strukturell komplexer Naturstoffe

SP Roche, JA Porco Jr - Angewandte Chemie, 2011 - Wiley Online Library
Abstract Auf dem Gebiet der Totalsynthese von Naturstoffen hat es in den vergangenen
zehn Jahren hochinteressante Entwicklungen gegeben. Zahlreiche chemoselektive und …

Metathesereaktionen in der Totalsynthese

KC Nicolaou, PG Bulger, D Sarlah - Angewandte Chemie, 2005 - Wiley Online Library
Abstract Mit Ausnahme der palladiumkatalysierten Kreuzkupplungsreaktionen hatte im
vergangenen Vierteljahrhundert keine Reaktionsklasse einen derart weitreichenden …

Furans and singlet oxygen–why there is more to come from this powerful partnership

T Montagnon, D Kalaitzakis, M Triantafyllakis… - Chemical …, 2014 - pubs.rsc.org
The purpose of this article is to give a taste of just how powerful the union between furans
and photochemically-generated singlet oxygen is proving to be as a synthetic tool and to …

Furans as versatile synthons: total syntheses of caribenol A and caribenol B

HD Hao, D Trauner - Journal of the American Chemical Society, 2017 - ACS Publications
Two complex norditerpenoids, caribenols A and B, were accessed from a common building
block. Our synthesis of caribenol A features the diastereoselective formation of the seven …