[HTML][HTML] SARS-CoV-2 vaccine-associated-tinnitus: a review
The global vaccination drive against severe acute respiratory syndrome coronavirus-2 is
being pursued at a historic pace. Unexpected adverse effects have been reported following …
being pursued at a historic pace. Unexpected adverse effects have been reported following …
Topical medication therapy for glaucoma and ocular hypertension
T Wang, L Cao, Q Jiang, T Zhang - Frontiers in Pharmacology, 2021 - frontiersin.org
Glaucoma is one of the most common causes of blindness, thus seriously affecting people's
health and quality of life. The topical medical therapy is as the first line treatment in the …
health and quality of life. The topical medical therapy is as the first line treatment in the …
NO as a multimodal transmitter in the brain: discovery and current status
J Garthwaite - British Journal of Pharmacology, 2019 - Wiley Online Library
NO operates throughout the brain as an intercellular messenger, initiating its varied
physiological effects by activating specialized GC‐coupled receptors, resulting in the …
physiological effects by activating specialized GC‐coupled receptors, resulting in the …
Peroxynitrite-Scavenging Organosilica Nanomedicines for Light-Controllable NO Release and Precision On-Demand Glaucoma Therapy
M Song, L Li, J Liu, Y Gao, M Li, L Zhou, B Qin… - ACS …, 2023 - ACS Publications
Nitric oxide (NO) is a promising approach for treating ocular hypertension and glaucoma.
However, its clinical application is limited by its uncontrollable release and the unwanted …
However, its clinical application is limited by its uncontrollable release and the unwanted …
Physiological function of myocilin and its role in the pathogenesis of glaucoma in the trabecular meshwork
H Wang, M Li, Z Zhang, H Xue… - … journal of molecular …, 2019 - spandidos-publications.com
Myocilin is highly expressed in the trabecular meshwork (TM), which plays an important role
in the regulation of intraocular pressure (IOP). Myocilin abnormalities may cause dysfunction …
in the regulation of intraocular pressure (IOP). Myocilin abnormalities may cause dysfunction …
Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma
Primary Open Angle Glaucoma (POAG) is the most common form of glaucoma that leads to
irreversible vision loss. Dysfunction of trabecular meshwork (TM) tissue, a major regulator of …
irreversible vision loss. Dysfunction of trabecular meshwork (TM) tissue, a major regulator of …
Identification of candidate miRNA biomarkers for glaucoma
AG Hindle, R Thoonen, JV Jasien… - … & visual science, 2019 - iovs.arvojournals.org
Purpose: Glaucoma, a leading cause of blindness worldwide, often remains undetected until
irreversible vision loss has occurred. Treatments focus on lowering intraocular pressure …
irreversible vision loss has occurred. Treatments focus on lowering intraocular pressure …
Design, Characterization and Pharmacokinetic–Pharmacodynamic Evaluation of Poloxamer and Kappa-Carrageenan-Based Dual-Responsive In Situ Gel of …
This study developed a dual-responsive in situ gel of nebivolol (NEB), a selective β-
adrenergic antagonist. The gel could achieve sustained concentrations in the aqueous …
adrenergic antagonist. The gel could achieve sustained concentrations in the aqueous …
Advances in understanding glaucoma pathogenesis: a multifaceted molecular approach for clinician scientists
Glaucoma, a leading cause of irreversible blindness worldwide, is a spectrum of
neurodegenerative diseases characterized by the gradual deterioration of retinal ganglion …
neurodegenerative diseases characterized by the gradual deterioration of retinal ganglion …
Endogenous dual stimuli-activated NO generation in the conventional outflow pathway for precision glaucoma therapy
W Fan, M Song, L Li, L Niu, Y Chen, B Han, X Sun… - Biomaterials, 2021 - Elsevier
High intraocular pressure (IOP) has been regarded as a predominant risk factor for
glaucoma. Nitric oxide (NO) is shown to lower IOP, but the magnitude and duration of IOP …
glaucoma. Nitric oxide (NO) is shown to lower IOP, but the magnitude and duration of IOP …