Cardiovascular disease (CVD) is a major cause of death in patients with chronic kidney
disease (CKD). Both conditions are rising in incidence as well as prevalence, creating poor …

Patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) have
significant cardiovascular morbidity and mortality that is in part due to the development of …

Vascular calcification is highly associated with cardiovascular disease mortality, particularly
in high-risk patients with diabetes and chronic kidney diseases (CKD). In blood vessels …

Background—Phenotypic switching of vascular smooth muscle cells from a contractile to a
synthetic state is implicated in diverse vascular pathologies, including atherogenesis …

In the elderly with atherosclerosis, hypertension and diabetes, vascular calcification and
ageing are ubiquitous. Melatonin (MT) has been demonstrated to impact the cardiovascular …

The importance of matrix vesicles (MVs) has been repeatedly highlighted in the formation of
cartilage, bone, and dentin since their discovery in 1967. These nano-vesicular structures …

Coronary artery calcification (CAC) is highly prevalent in patients with coronary heart
disease (CHD) and is associated with major adverse cardiovascular events. There are two …

Arterial calcification is highly prevalent, particularly in patients with end-stage renal disease
(ESRD). The osteogenic differentiation of vascular smooth muscle cells (VSMCs) is the …

Background Emerging evidences have indicated that long non-coding RNAs (lncRNAs) play
vital roles in cardiovascular physiology and pathology. The lncRNA MALAT1, a highly …

Pulmonary hypertension (PH) is a progressive disease that arises from multiple etiologies
and ultimately leads to right heart failure as the predominant cause of morbidity and …