[HTML][HTML] Cyclooxygenase-1 (COX-1) and COX-1 inhibitors in cancer: A review of oncology and medicinal chemistry literature

A Pannunzio, M Coluccia - Pharmaceuticals, 2018 - mdpi.com
Prostaglandins and thromboxane are lipid signaling molecules deriving from arachidonic
acid by the action of the cyclooxygenase isoenzymes COX-1 and COX-2. The role of …

Progress in COX-2 inhibitors: a journey so far

AK Chakraborti, SK Garg, R Kumar… - Current medicinal …, 2010 - ingentaconnect.com
The non-steroidal anti-inflammatory drugs (NSAIDs) are diverse group of compounds used
for the treatment of inflammation, since the introduction of acetylsalicylic acid in 1899 …

Amygdalin induces apoptosis in human cervical cancer cell line HeLa cells

YU Chen, J Ma, F Wang, J Hu, A Cui… - …, 2013 - Taylor & Francis
Amygdalin, a naturally occurring substance, has been suggested to be efficacious as an
anticancer substance. The effect of amygdalin on cervical cancer cells has never been …

Silica-lipid hybrid (SLH) microcapsules: a novel oral delivery system for poorly soluble drugs

A Tan, S Simovic, AK Davey, T Rades… - Journal of controlled …, 2009 - Elsevier
A silica-lipid hybrid (SLH) microcapsule system for oral delivery of poorly water-soluble
drugs is reported for the first time. For the model drug celecoxib (CEL), SLH microcapsules …

[HTML][HTML] Antiinflammatory Medicinal Plants from the Ugandan Greater Mpigi Region Act as Potent Inhibitors in the COX-2/PGH2 Pathway

F Schultz, OF Osuji, B Wack, G Anywar, LA Garbe - Plants, 2021 - mdpi.com
Our study investigates 16 medicinal plants via assessment of inhibition of proinflammatory
enzymes such as cyclooxygenases (COX). The plants are used by traditional healers in the …

[HTML][HTML] Hippocampal over-expression of cyclooxygenase-2 (COX-2) is associated with susceptibility to stress-induced anhedonia in mice

T Strekalova, D Pavlov, A Trofimov… - International journal of …, 2022 - mdpi.com
The phenomenon of individual variability in susceptibility/resilience to stress and
depression, in which the hippocampus plays a pivotal role, is attracting increasing attention …

Oral diindolylmethane (DIM): pilot evaluation of a nonsurgical treatment for cervical dysplasia

G Del Priore, DK Gudipudi, N Montemarano… - Gynecologic …, 2010 - Elsevier
OBJECTIVE: Standard surgical treatment for CIN may impair fertility generating a need for
alternative treatment options. We tested the efficacy and toxicity of oral DIM in the treatment …

[HTML][HTML] Emerging biological treatments for uterine cervical carcinoma

P Vici, L Mariani, L Pizzuti, D Sergi, L Di Lauro… - Journal of …, 2014 - ncbi.nlm.nih.gov
Cervical cancer is the third most common cancer worldwide, and the development of new
diagnosis, prognostic, and treatment strategies is a major interest for public health. Cisplatin …

Regulation of immune responses to HPVinfection and during HPV‐directed immunotherapy

P Bhat, SR Mattarollo, C Gosmann… - Immunological …, 2011 - Wiley Online Library
The recent development of vaccines prophylactic against human papillomavirus (HPV)
infection has the potential to reduce the incidence of cervical cancer globally by up to 70 …

[HTML][HTML] Innate immunity and HPV: friends or foes

RAL Nunes, MG Morale, GÁF Silva, LL Villa, L Termini - Clinics, 2018 - SciELO Brasil
Most human papillomavirus infections are readily cleared by the host immune response.
However, in some individuals, human papillomavirus can establish a persistent infection …