Cancer is the second leading cause of death in the world and one of the major public health
problems. Despite the great advances in cancer therapy, the incidence and mortality rates of …

Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling mediates
almost all immune regulatory processes, including those that are involved in tumor cell …

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that
regulates various biological processes, including proliferation, metastasis, angiogenesis …

Parkinson's disease (PD) is a slowly progressive multisystem disorder affecting
dopaminergic neurons of the substantia nigra pars compacta (SNpc), which is characterized …

Cancer is a major burden of disease globally. Each year, tens of millions of people are
diagnosed with cancer worldwide, and more than half of the patients eventually die from it …

Abstract Coronavirus disease-19 (COVID-19), a devastating respiratory illness caused by
SARS-associated coronavirus-2 (SARS-CoV-2), has already affected over 64 million people …

Cancer continues to cause an alarming number of deaths globally, and its burden on the
health system is significant. Though different conventional therapeutic procedures are …

Signal transducer and activator of transcription 3 (STAT3) plays a critical role in signal
transmission from the plasma membrane to the nucleus, regulating the expression of genes …

Transcription factors have roles at focal points in signaling pathways, controlling many
normal cellular processes, such as cell growth and proliferation, metabolism, apoptosis …

Cytokines are small signaling proteins that have central roles in inflammation and cell
survival. In the half-century since the discovery of the first cytokines, the interferons, over fifty …