The roles and regulation of the KLF5 transcription factor in cancers
Y Luo, C Chen - Cancer science, 2021 - Wiley Online Library
Krüppel‐like factor 5 (KLF5) is a member of the KLF family. Recent studies have suggested
that KLF5 regulates the expression of a large number of new target genes and participates …
that KLF5 regulates the expression of a large number of new target genes and participates …
CRISPR/Cas9 system in breast cancer therapy: advancement, limitations and future scope
V Karn, S Sandhya, W Hsu, D Parashar… - Cancer Cell …, 2022 - Springer
Cancer is one of the major causes of mortality worldwide, therefore it is considered a major
health concern. Breast cancer is the most frequent type of cancer which affects women on a …
health concern. Breast cancer is the most frequent type of cancer which affects women on a …
LncRNA LUCAT1 facilitates tumorigenesis and metastasis of triple-negative breast cancer through modulating miR-5702
E Mou, H Wang - Bioscience reports, 2019 - portlandpress.com
Triple-negative breast cancer (TNBC) is a subtype of aggressive breast cancer with high
recurrence and poor survival. Emerging evidence has indicated that long non-coding RNAs …
recurrence and poor survival. Emerging evidence has indicated that long non-coding RNAs …
Identification of hub genes to regulate breast cancer metastasis to brain by bioinformatics analyses
D Tang, X Zhao, LI Zhang, Z Wang… - Journal of Cellular …, 2019 - Wiley Online Library
Breast cancer with metastasis especially brain metastasis represents a significant cause of
morbidity and mortality in patients. In this study, we aimed to investigate the hub genes and …
morbidity and mortality in patients. In this study, we aimed to investigate the hub genes and …
Intercellular adhesion molecule-1 as target for CAR-T-cell therapy of triple-negative breast cancer
H Wei, Z Wang, Y Kuang, Z Wu, S Zhao… - Frontiers in …, 2020 - frontiersin.org
Triple-negative breast cancer (TNBC) comprises lethal malignancies with limited treatment
options. Chimeric antigen receptor T (CAR-T) cell therapy is an effective immunotherapeutic …
options. Chimeric antigen receptor T (CAR-T) cell therapy is an effective immunotherapeutic …
Exploring the causality and pathogenesis of systemic lupus erythematosus in breast cancer based on Mendelian randomization and transcriptome data analyses
W Li, R Wang, W Wang - Frontiers in Immunology, 2023 - frontiersin.org
Introduction There has been a cumulative interest in relationships between systemic lupus
erythematosus (SLE) and cancer risk. Breast cancer is the most common cancer among …
erythematosus (SLE) and cancer risk. Breast cancer is the most common cancer among …
Immune-related biomarkers predict the prognosis and immune response of breast cancer based on bioinformatic analysis and machine learning
X Zheng, H Ma, Y Dong, M Fang, J Wang… - Functional & Integrative …, 2023 - Springer
Breast cancer (BC) is the malignancy with the highest mortality rate among women,
identification of immune-related biomarkers facilitates precise diagnosis and improvement of …
identification of immune-related biomarkers facilitates precise diagnosis and improvement of …
[HTML][HTML] CRISPR/Cas9 based genome editing for targeted transcriptional control in triple-negative breast cancer
Breast cancer (BC) is the most common type of cancer in women at the global level and the
highest mortality rate has been observed with triple-negative breast cancer (TNBC) …
highest mortality rate has been observed with triple-negative breast cancer (TNBC) …
Expression of cancer–testis antigens in esophageal cancer and their progress in immunotherapy
Y Zhang, Y Zhang, L Zhang - Journal of cancer research and clinical …, 2019 - Springer
Purpose Esophageal cancer is a common disease in China with low survival rate due to no
obvious early symptoms and lack of effective screening strategies. Traditional treatments …
obvious early symptoms and lack of effective screening strategies. Traditional treatments …
Integrated multi-omics analyses and functional validation reveal TTK as a novel EMT activator for endometrial cancer
Y Miao, Y Konno, B Wang, L Zhu, T Zhai, K Ihira… - Journal of Translational …, 2023 - Springer
Abstract Background Cancer-testis antigens (CTAs) are often expressed in tumor and
testicular tissues but not in other normal tissues. To date, there has been no comprehensive …
testicular tissues but not in other normal tissues. To date, there has been no comprehensive …