Background and Purpose: Population-wide reductions in cardiovascular disease incidence
and mortality have not been shared equally by African Americans. The burden of …

Importance Systematic reviews and meta-analyses of individual participant data (IPD) aim to
collect, check, and reanalyze individual-level data from all studies addressing a particular …

Every 5 years, the JAS publishes guidelines for the treatment of dyslipidemia and
atherosclerosis. To date, this society has released four such guidelines. Since 2007, the JAS …

Atherosclerotic cardiovascular diseases (ASCVD), including coronary artery disease,
cerebrovascular disease, and peripheral arterial disease, represent a significant cause of …

Fibrinogen conversion into insoluble fibrin and the formation of a stable clot is the final step
of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated …

Fibrinogen is an abundant protein synthesized in the liver, present in human blood plasma
at concentrations ranging from 1.5-4 g/L in healthy individuals with a normal half-life of 3-5 …

Background There is debate about the value of assessing levels of C-reactive protein (CRP)
and other biomarkers of inflammation for the prediction of first cardiovascular events …

Aims Because low-grade inflammation may play a role in the pathogenesis of coronary heart
disease (CHD), and pro-inflammatory cytokines govern inflammatory cascades, this study …

A link between oral health and cardiovascular disease has been proposed for more than a
century. Recently, concern about possible links between periodontal disease (PD) and …

Background The extent to which diabetes mellitus or hyperglycemia is related to risk of
death from cancer or other nonvascular conditions is uncertain. Methods We calculated …