Aluminum-containing adjuvants have been used for over 90 years to enhance the immune
response to vaccines. Recent work has significantly advanced our understanding of the …

Metals are essential components in all forms of life required for the function of nearly half of
all enzymes and are critically involved in virtually all fundamental biological processes …

The immune system plays a critical role in our health. No other component of human
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …

Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

Adjuvants are used in many vaccines, but their mechanisms of action are not fully
understood. Studies from the past decade on adjuvant mechanisms are slowly revealing the …

In spite of current influenza vaccines being immunogenic, evolution of the influenza virus
can reduce efficacy and so influenza remains a major threat to public health. One approach …

Vaccination is a groundbreaking approach in preventing and controlling infectious diseases.
However, the effectiveness of vaccines can be greatly enhanced by the inclusion of …

Researchers working on the development of vaccines face an inherent dilemma: to
maximize immunogenicity without compromising safety and tolerability. Early vaccines often …

Aluminum (Al) is a ubiquitous substance encountered both naturally (as the third most
abundant element) and intentionally (used in water, foods, pharmaceuticals, and vaccines); …

Dendritic cell (DC)‐based cancer immunotherapy has exhibited remarkable clinical
prospects because DCs play a central role in initiating and regulating adaptive immune …