The emerging role of lncRNAs in the regulation of cancer stem cells

R Castro-Oropeza, J Melendez-Zajgla, V Maldonado… - Cellular Oncology, 2018 - Springer
Background Tumors contain a functional subpopulation of cells that exhibit stem cell
properties. These cells, named cancer stem cells (CSCs), play significant roles in the …

Targeting microRNAs in cancer gene therapy

W Ji, B Sun, C Su - Genes, 2017 - mdpi.com
MicroRNAs (miRNAs) are a kind of conserved small non-coding RNAs that participate in
regulating gene expression by targeting multiple molecules. Early studies have shown that …

[HTML][HTML] MiR-145: a potential biomarker of cancer migration and invasion

WX Xu, Z Liu, F Deng, DD Wang, XW Li… - American journal of …, 2019 - ncbi.nlm.nih.gov
MircoRNAs (miRNAs) are a diverse family of highly-conserved small non-coding RNAs,
which range from approximately 18 to 25 nucleotides in size. They regulate gene expression …

The crucial role of ZEB2: from development to epithelial‐to‐mesenchymal transition and cancer complexity

M Fardi, M Alivand, B Baradaran… - Journal of cellular …, 2019 - Wiley Online Library
Zinc finger E‐box binding homeobox 2 (ZEB2) is a DNA‐binding transcription factor, which
is mainly involved in epithelial‐to‐mesenchymal transition (EMT). EMT is a conserved …

Cervical cancer markers: epigenetics and microRNAs

V Laengsri, U Kerdpin, C Plabplueng… - Laboratory …, 2018 - academic.oup.com
Gynecologic malignant neoplasms are a severe health problem among female patients, of
which cervical cancer (CC), in particular, is a common disease leading to high mortality …

The role of miRNAs in the invasion and metastasis of cervical cancer

J Wang, L Chen - Bioscience reports, 2019 - portlandpress.com
Cervical cancer (CC) with early metastasis of the primary tumor results in poor prognosis
and poor therapeutic outcomes. MicroRNAs (miRNAs) are small, noncoding RNA molecules …

Cervical cancer development, chemoresistance, and therapy: a snapshot of involvement of microRNA

T Mitra, S Elangovan - Molecular and Cellular Biochemistry, 2021 - Springer
Cervical cancer (CC) is one of the leading causes of death in women due to cancer and a
major concern in the developing world. Persistent human papilloma virus (HPV) infection is …

MicroRNA-92a promotes epithelial-mesenchymal transition through activation of PTEN/PI3K/AKT signaling pathway in non-small cell lung cancer metastasis

C Lu, Z Shan, J Hong, L Yang - … journal of oncology, 2017 - spandidos-publications.com
MicroRNAs (miRNAs) have important roles in various cancers, including non-small cell lung
cancer (NSCLC). Although several miRNAs have reported to be involved in the …

Targeting epithelial–mesenchymal plasticity in cancer: clinical and preclinical advances in therapy and monitoring

S Bhatia, J Monkman, AKL Toh, SH Nagaraj… - Biochemical …, 2017 - portlandpress.com
The concept of epithelial–mesenchymal plasticity (EMP), which describes the dynamic flux
within the spectrum of phenotypic states that invasive carcinoma cells may reside, is being …

miR‐145 inhibits aerobic glycolysis and cell proliferation of cervical cancer by acting on MYC

C Hu, T Liu, W Zhang, Y Sun, D Jiang… - The FASEB …, 2023 - Wiley Online Library
Nearly half a million women are diagnosed with cervical cancer (CC) each year, with the
incidence of CC stabilizing or rising in low‐income and middle‐income countries. Cancer …