Quantitative computed tomography is being increasingly used to quantify the features of
chronic obstructive pulmonary disease, specifically emphysema, air trapping, and airway …

The purpose of this statement is to describe and define the phenotypic abnormalities that
can be identified on visual and quantitative evaluation of computed tomographic (CT) …

Autopsy studies in fatal asthma have clearly documented the central role of airway plugging
with pathologic mucus in the pathophysiology of death from asthma, but the role of mucus …

Multidetector row computed tomography (MDCT) is increasingly taking a central role in
identifying subphenotypes within chronic obstructive pulmonary disease (COPD), asthma …

The Biomarkers Definitions Working Group defines a clinical endpoint as a variable that
reflects how a patient feels, functions, or survives (5, 6). The past 3 decades of IPF clinical …

We evaluated performance characteristics and estimated the minimal clinically important
difference (MCID) of data-driven texture analysis (DTA), a high-resolution computed …

Background Currently, there is limited knowledge regarding which imaging assessments of
asthma are associated with accelerated longitudinal decline in lung function. Objectives We …

Objectives The purpose of this study was to evaluate the impact of ultralow radiation dose
single-energy computed tomographic (CT) acquisitions with Sn prefiltration and third …

Background: Low lung function is known to predict mortality in the general population, but
the prognostic significance of emphysema on computed tomography (CT) in persons without …

Objectives To evaluate a semi-automated segmentation and ventilated lung quantification
on chest computed tomography (CT) to assess lung involvement in patients affected by …