Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Objectives: Cardiac surgery, including coronary artery bypass, cardiac valve, and aortic
procedures, is among the most common surgical procedures performed in the United States …

Objectives: During circulatory failure, the ultimate goal of treatments that increase cardiac
output is to reduce tissue hypoxia. This can only occur if oxygen consumption depends on …

Introduction Since normal or high central venous oxygen saturation (ScvO 2) values cannot
discriminate if tissue perfusion is adequate, integrating other markers of tissue hypoxia, such …

Background To evaluate the ability of the central venous-to-arterial CO 2 content and
tension differences to arteriovenous oxygen content difference ratios (∆ ContCO 2/∆ ContO 2 …

Introduction In septic shock patients, the prevalence of low (< 70%) central venous oxygen
saturation (ScvO2) on admission to the intensive care unit (ICU) and its relationship to …

Objective To investigate the use of oxygen metabolism markers as predictors of mortality in
patients with severe coronavirus disease 2019 (COVID-19). Methods A retrospective …

Background Optical spectroscopy is commonly used clinically to monitor oxygen saturation
in tissue. The most commonly employed technique is pulse oximetry, which provides a point …

Objective The current practice in treatment of severe sepsis and septic shock is to ensure
adequate oxygenation and perfusion in patients, along with prompt administration of …

Preexisting heart failure (HF) in patients with sepsis is associated with worse clinical
outcomes. Core sepsis management includes aggressive volume resuscitation followed by …