Reaction–diffusion waves in biology

V Volpert, S Petrovskii - Physics of life reviews, 2009 - Elsevier
The theory of reaction–diffusion waves begins in the 1930s with the works in population
dynamics, combustion theory and chemical kinetics. At the present time, it is a well …

Cell population heterogeneity and evolution towards drug resistance in cancer: biological and mathematical assessment, theoretical treatment optimisation

RH Chisholm, T Lorenzi, J Clairambault - Biochimica et Biophysica Acta …, 2016 - Elsevier
Background Drug-induced drug resistance in cancer has been attributed to diverse
biological mechanisms at the individual cell or cell population scale, relying on …

[图书][B] Analysis of evolutionary processes: the adaptive dynamics approach and its applications: the adaptive dynamics approach and its applications

F Dercole, S Rinaldi - 2008 - degruyter.com
Quantitative approaches to evolutionary biology traditionally consider evolutionary change
in isolation from an important pressure in natural selection: the demography of coevolving …

Populational adaptive evolution, chemotherapeutic resistance and multiple anti-cancer therapies

A Lorz, T Lorenzi, ME Hochberg… - … et Analyse Numérique, 2013 - numdam.org
Resistance to chemotherapies, particularly to anticancer treatments, is an increasing
medical concern. Among the many mechanisms at work in cancers, one of the most …

Dirac mass dynamics in multidimensional nonlocal parabolic equations

A Lorz, S Mirrahimi, B Perthame - Communications in Partial …, 2011 - Taylor & Francis
Nonlocal Lotka–Volterra models have the property that solutions concentrate as Dirac
masses in the limit of small diffusion. Is it possible to describe the dynamics of the limiting …

Invasion fronts with variable motility: phenotype selection, spatial sorting and wave acceleration

E Bouin, V Calvez, N Meunier, S Mirrahimi… - Comptes Rendus …, 2012 - numdam.org
Dans un second temps, nous considérons un espace des traits non borné, Θ=+∞. Dans ce
cas le front accélère sans cesse et nous montrons heuristiquement que la loi de propagation …

Dirac concentrations in lotka-volterra parabolic pdes

B Perthame, G Barles - Indiana University Mathematics Journal, 2008 - JSTOR
We consider parabolic partial differential equations of Lotka-Volterra type, with a non-local
nonlinear term. This models, at the population level, the darwinian evolution of a population; …

On selection dynamics for continuous structured populations

L Desvillettes, PE Jabin, S Mischler, G Raoul - 2008 - projecteuclid.org
ON SELECTION DYNAMICS FOR CONTINUOUS STRUCTURED POPULATIONS∗ 1.
Introduction We are concerned with nonlinear selection (or com Page 1 COMMUN. MATH. SCI. c …

Concentration in Lotka-Volterra parabolic or integral equations: a general convergence result

G Barles, S Mirrahimi, B Perthame - 2009 - projecteuclid.org
We study two equations of Lotka-Volterra type that describe the Darwinian evolution of a
population density. In the first model a Laplace term represents the mutations. In the second …

[HTML][HTML] Asymptotic analysis and optimal control of an integro-differential system modelling healthy and cancer cells exposed to chemotherapy

C Pouchol, J Clairambault, A Lorz, E Trélat - Journal de Mathématiques …, 2018 - Elsevier
We consider a system of two coupled integro-differential equations modelling populations of
healthy and cancer cells under chemotherapy. Both populations are structured by a …