Substance use in young people (aged 10–24 years) might disrupt key periods of transition
that occur as the adolescent brain undergoes cognitive and emotional development, and …

We did a systematic review of reviews with evidence on the effectiveness of prevention,
early intervention, harm reduction, and treatment of problem use in young people for …

Background and aims Adolescent alcohol misuse is a growing global health concern.
Substantial research suggests that parents have an important role in reducing young …

In many high-income countries, the proportion of adolescents who smoke, drink, or engage
in other risk behaviours has declined markedly over the past 25 years. We illustrate this …

Adolescents detained within the criminal justice system are affected by complex health
problems, health-risk behaviours, and high rates of premature death. We did a global …

Currently, a proportion of adolescents use alcohol, tobacco, and illicit drugs, which inevitably
harms their health and academic progress. Adolescence is a peak period for substance use …

Importance Recent information on the trends in past-year alcohol abstinence and marijuana
abstinence, co-use of alcohol and marijuana, alcohol use disorder, and marijuana use …

Background Engagement in multiple risk behaviours can have adverse consequences for
health during childhood, during adolescence, and later in life, yet little is known about the …

Background Child mental health problems are common. Previous studies have examined
secular changes in their prevalence but have not assessed whether later outcomes have …

The main objective of this prospective longitudinal study was to investigate bidirectional
associations between adolescent cannabis use (CU) and neurocognitive performance in a …