As an anti-adhesive, a reservoir for key biological molecules, and a modulator of signaling,
polysialic acid (polySia) is critical for nervous system development and maintenance …

Sialic acids (Sia) are involved in many biological activities and frequently exist as monosialyl
residues at the non-reducing terminal end of glycoconjugates. Occasionally, polymerized …

This review is the sixth update of the original article published in 1999 on the application of
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …

Sialic acids are a family of 9-carbon monosaccharides with particular physicochemical
properties. They modulate the biological functions of the molecules that carry them and are …

Sialidases are glycohydrolytic enzymes present from virus to mammals that remove sialic
acid from oligosaccharide chains. Four different sialidase forms are known in vertebrates …

Glycan structures in non-vertebrates are highly variable; it can be assumed that this is a
product of evolution and speciation, not that it is just a random event. However, in animals …

Glycosylation of proteins and lipids occurs in vertebrates, usually terminating with sialylation,
which regulates the physicochemical and biological properties of these glycoconjugates …

Although the structural diversity of sialic acid (Sia) is rapidly expanding, understanding of its
biological significance has lagged behind. Advanced technologies to detect and probe …

Glycobiology is the study of complex carbohydrates in biological systems and represents a
developing field of science that has made huge advances in the last half century. In fact, it …

Echinoderms are among the most primitive deuterostomes and have been used as model
organisms to understand chordate biology because of their close evolutionary relationship …