The aging and elderly population are particularly susceptible to cardiovascular disease. Age
is an independent risk factor for cardiovascular disease (CVD) in adults, but these risks are …

Acute lung injury in humans is characterized histopathologically by neutrophilic alveolitis,
injury of the alveolar epithelium and endothelium, hyaline membrane formation, and …

Reactive oxygen or nitrogen species (ROS/RNS) generated endogenously or in response to
environmental stress have long been implicated in tissue injury in the context of a variety of …

In clinical settings, oxygen therapy is administered to preterm neonates and to adults with
acute and chronic conditions such as COVID-19, pulmonary fibrosis, sepsis, cardiac arrest …

Oxygen administration is uniformly used in emergency and intensive care medicine and has
life-saving potential in critical conditions. However, excessive oxygenation also has …

The primary function of neutrophils in host defense is to contain and eradicate invading
microbial pathogens. This is achieved through a series of swift and highly coordinated …

The angiogenic growth factor angiopoietin 2 (Ang2) destabilizes blood vessels, enhances
vascular leak and induces vascular regression and endothelial cell apoptosis. We …

The goals of this study were to determine whether the Fas-dependent apoptosis pathway is
active in the lungs of patients with the acute respiratory distress syndrome (ARDS), and …

Background Studies investigating the role of hyperoxia in critically ill patients have reported
conflicting results. We did this analysis to reveal the effect of hyperoxia in the patients …

Exposure to asbestos causes cellular damage, leading to asbestosis, bronchogenic
carcinoma, and mesothelioma in humans. The pathogenesis of asbestos-related diseases is …