Chlamydia trachomatis serovars are obligate intracellular bacterial pathogens mainly
causing ocular and urogenital infections that affect millions of people worldwide and which …

Chlamydia trachomatis (Ct) is an intracellular bacterial pathogen that relies on the activity of
secreted proteins known as effectors to promote replication and avoidance of immune …

Many microbes create and maintain pathogen-containing vacuoles (PVs) as an intracellular
niche permissive for microbial growth and survival. The destruction of PVs by IFNγ-inducible …

Gene inactivation by transposon insertion or allelic exchange is a powerful approach to
probe gene function. Unfortunately, many microbes, including Chlamydia, are not amenable …

The chlamydial cryptic plasmid encodes eight putative open reading frames (ORFs),
designated pORF1 to-8. Antibodies raised against these ORF proteins were used to localize …

Many intracellular pathogens rely on host cell membrane compartments for their survival.
The strategies they have developed to subvert intracellular trafficking are often unknown …

Background Chlamydiae are obligate intracellular bacteria that multiply in a vacuolar
compartment, the inclusion. Several chlamydial proteins containing a bilobal hydrophobic …

Although the Chlamydia trachomatis genome is predicted to encode 50 inclusion membrane
proteins, only 18 have been experimentally localized in the inclusion membrane of C …

Chlamydia trachomatis infection induces inflammatory pathologies in the upper genital tract,
potentially leading to ectopic pregnancy and infertility in the affected women. Caspase-1 is …

OBJECTIVE: To identify Chlamydia trachomatis antigens associated with tubal factor
infertility and acute infection. METHODS: AC trachomatis proteome array was used to …