Contribution of oxidative stress in the mechanisms of postoperative complications and multiple organ dysfunction syndrome

J Toro-Pérez, R Rodrigo - Redox Report, 2021 - Taylor & Francis
Background The extent of the damage following surgery has been subject of study for
several years. Numerous surgical complications can impact postoperative quality of life of …

[HTML][HTML] Renal delivery of pharmacologic agents during machine perfusion to prevent ischaemia-reperfusion injury: from murine model to clinical trials

R Franzin, A Stasi, M Fiorentino, S Simone… - Frontiers in …, 2021 - frontiersin.org
Donor organ shortage still remains a serious obstacle for the access of wait-list patients to
kidney transplantation, the best treatment for End-Stage Kidney Disease (ESKD). To expand …

Renalase contributes to protection against renal fibrosis via inhibiting oxidative stress in rats

Y Wu, L Wang, X Wang, Y Wang, Q Zhang… - International urology and …, 2018 - Springer
Background Renal interstitial fibrosis (RIF) is a common pathway for progression of chronic
kidney disease (CKD) to end-stage renal disease. In our previous study, it has been …

[HTML][HTML] Combating ischemia-reperfusion injury with micronutrients and natural compounds during solid organ transplantation: Data of clinical trials and lessons of …

C Mauerhofer, L Grumet, P Schemmer, B Leber… - International Journal of …, 2021 - mdpi.com
Although extended donor criteria grafts bear a higher risk of complications such as graft
dysfunction, the exceeding demand requires to extent the pool of potential donors. The risk …

[HTML][HTML] Elevated plasma free thiols are associated with early and one-year graft function in renal transplant recipients

MB Nielsen, B Jespersen, H Birn, NV Krogstrup… - PLoS …, 2021 - journals.plos.org
Background Reduced free thiols in plasma are indicative of oxidative stress, which is an
important contributor to ischaemia-reperfusion injury (IRI) in kidney transplantation leading …

Donor Dependent Variations in Systemic Oxidative Stress and Their Association with One-Year Graft Outcomes In Kidney Transplantation

E Rodriguez-Sanchez, J Aceves-Ripoll… - American journal of …, 2024 - karger.com
Introduction: Oxidative stress has been implicated in complications after kidney
transplantation (KT), including delayed graft function and rejection. However, its role in long …

[HTML][HTML] Plasma malondialdehyde and risk of new-onset diabetes after transplantation in renal transplant recipients: a prospective cohort study

M Yepes-Calderón, CG Sotomayor… - Journal of Clinical …, 2019 - mdpi.com
New-onset diabetes after transplantation (NODAT) is a frequent complication in renal
transplant recipients (RTR). Although oxidative stress has been associated with diabetes …

Urinary oxylipin signature as biomarkers to monitor the allograft function during the first six months post-renal transplantation

S Medina, I De las Heras-Gomez, T Casas-Pina… - Free Radical Biology …, 2020 - Elsevier
Oxylipins such as isoprostanes (IsoPs), prostaglandins (PGs) and thromboxanes (TXs) are
lipid mediators derived from the oxidation of polyunsaturated fatty acids, which regulate the …

[PDF][PDF] Role of ischemia-reperfusion in oxidative stress-mediated injury during kidney transplantation

C Ávila, L Líbano, I Rojas, R Rodrigo - Clinical Research, 2019 - academia.edu
Renal transplant (RT) is the definitive treatment for end-stage renal disease, which is known
as a high prevalence pathology with strong economic repercussion both for patients and …

[HTML][HTML] Proteoglycan binding as proatherogenic function metric of apoB-containing lipoproteins and chronic kidney graft failure

HLM Steffen, JLC Anderson, ML Poot, Y Lei… - Journal of lipid …, 2021 - ASBMB
Lipoprotein-proteoglycan binding is an early key event in atherosclerotic lesion formation
and thus conceivably could play a major role in vasculopathy-driven chronic graft failure and …