Conspectus This Account summarizes the progress in protein–calixarene complexation,
tracing the developments from binary recognition to the glue activity of calixarenes and …

Lysine-selective molecular tweezers (MTs) are supramolecular host molecules displaying a
remarkably broad spectrum of biologic activities. MTs act as inhibitors of the self-assembly …

The specific recognition of protein surface elements is a fundamental challenge in the life
sciences. New developments in this field will form the basis of advanced therapeutic …

Photocatalysis holds great promise for changing the way value-added molecules are
currently prepared. However, many photocatalytic reactions suffer from quantum yields well …

Controlled protein assembly provides a means to regulate function. Supramolecular building
blocks, including rigid macrocycles, are versatile triggers of protein assembly. Now it is …

Synthetic macrocycles such as calixarenes and cucurbiturils are increasingly applied as
mediators of protein assembly and crystallization. The macrocycle can facilitate assembly by …

Complex formation between cationic cytochrome c and the water‐soluble, poly‐anionic p‐
phosphonatocalix [6] arene (pclx6) was investigated. A crystal structure (at 1.8 Å resolution) …

Survivin's dual function as apoptosis inhibitor and regulator of cell proliferation is mediated
via its interaction with the export receptor CRM1. This protein–protein interaction represents …

Protein crystallization remains a serious bottleneck to structure determination by X-ray
diffraction methods. Compounds acting as “molecular glue” provide a promising strategy to …

Calixarenes are displaying great potential for the development of new drug delivery
systems, diagnostic imaging, biosensing devices and inhibitors of biological processes. In …