Owing to its high disability and mortality rates, stroke has been the second leading cause of
death worldwide. Since the pathological mechanisms of stroke are not fully understood …

Ischemic stroke remains a leading cause of morbidity and disability around the world. The
sequelae of serious neurological damage are irreversible due to body's own limited repair …

The supply of oxygen and nutrients to the brain is vital for its function and requires a complex
vascular network that, when disturbed, results in profound neurological dysfunction. As part …

Ischemic stroke is a major condition that remains extremely problematic to treat. A cerebral
reperfusion injury becomes apparent after an ischemic accident when reoxygenation of the …

Stroke is a devastating medical condition with no treatment to hasten recovery. Its abrupt
nature results in cataclysmic changes in the affected tissues. Resident cells fail to cope with …

Brain microvascular endothelial cell (BMEC) survival and angiogenesis after ischemic stroke
has great significance for improving the prognosis of stroke. Abnormal variants of lncRNAs …

Cerebral ischemic injury exhibits both high morbidity and mortality worldwide. Traditional
research of the pathogenesis of cerebral ischemic injury has focused on separate analyses …

Aim: Hepatic ischemia-reperfusion (HIR) induces remote organs injury, including the brain.
The homeostasis of the brain is maintained by the blood-brain barrier (BBB); thus, we aimed …

Ischemic stroke (IS) is the predominant subtype of stroke and a leading contributor to global
mortality. The mitochondrial-associated endoplasmic reticulum membrane (MAM) is a …

Spliced X-box binding protein-1 (XBP1s) is a protein that belongs to the cAMP-response
element-binding (CREB)/activating transcription factor (ATF) b-ZIP family with a basic-region …