Kraepelin, in his early descriptions of schizophrenia (SZ), characterized the illness as having
“an orchestra without a conductor.” Kraepelin further speculated that this “conductor” was …

Oxidative stress, which results in the damage of diverse biological molecules, is a ubiquitous
cellular process implicated in the etiology of many illnesses. The sulfhydryl-containing …

Background Schizophrenia (SCZ) is a severe psychiatric disorder that involves inflammatory
processes. The aim of this study was to explore the field of inflammation-related research in …

Schizophrenia, a multisystem disorder with an unknown etiology, is associated with several
immune dysfunctions, including abnormal levels of circulating cytokines. In this review, we …

Neuroinflammation, particularly in the dorsolateral prefrontal cortex, is well-established in a
subset of people with schizophrenia, with significant increases in inflammatory markers …

Background Impairment in a wide range of cognitive abilities has been consistently reported
in individuals with schizophrenia. Both neurocognitive and social cognitive deficits are …

Increasing evidence suggests estrogen and estrogen signaling pathway disturbances
across psychiatric disorders. Estrogens are not only crucial in sexual maturation and …

Importance Schizophrenia is associated with cognitive dysfunction and cardiovascular risk
factors, including metabolic syndrome (MetS) and its constituent criteria. Cognitive …

Objective Antipsychotic effects of immunomodulating drugs have been suggested; however,
a thorough, comprehensive meta-analysis on the effect and safety of anti-inflammatory add …

Background: Inflammation plays a major role in the onset and maintenance of
schizophrenia. The objective of the present work was to synthetize in a narrative review the …