Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology

E Schrezenmeier, T Dörner - Nature Reviews Rheumatology, 2020 - nature.com
Despite widespread clinical use of antimalarial drugs such as hydroxychloroquine and
chloroquine in the treatment of rheumatoid arthritis (RA), systemic lupus erythematosus …

Novel paradigms in systemic lupus erythematosus

T Dörner, R Furie - The Lancet, 2019 - thelancet.com
The heterogeneity of systemic lupus erythematosus (SLE), long recognised by clinicians, is
now challenging the entire lupus community, from geneticists to clinical investigators …

Guidelines on the Use of therapeutic apheresis in clinical practice–Evidence‐Based approach from the Writing Committee of the American Society for Apheresis: The …

L Connelly‐Smith, CR Alquist, NA Aqui… - Journal of clinical …, 2023 - Wiley Online Library
Abstract The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA)
Special Issue Writing Committee is charged with reviewing, updating, and categorizing …

Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial

Z Chen, J Hu, Z Zhang, S Jiang, S Han, D Yan… - medrxiv, 2020 - medrxiv.org
Aims Studies have indicated that chloroquine (CQ) shows antagonism against COVID-19 in
vitro. However, evidence regarding its effects in patients is limited. This study aims to …

Hydroxychloroquine in systemic lupus erythematosus: overview of current knowledge

A Dima, C Jurcut, F Chasset… - Therapeutic …, 2022 - journals.sagepub.com
The antimalarial hydroxychloroquine (HCQ) has demonstrated several crucial properties for
the treatment of systemic lupus erythematosus (SLE). Herein, we reviewed the main HCQ …

Effectiveness of belimumab after rituximab in systemic lupus erythematosus: a randomized controlled trial

M Shipa, A Embleton-Thirsk, M Parvaz… - Annals of internal …, 2021 - acpjournals.org
Background: B-cell depletion with rituximab is commonly used for patients with systemic
lupus erythematosus (SLE) that is refractory to conventional therapy, but it yields variable …

British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids

MD Russell, M Dey, J Flint, P Davie, A Allen… - …, 2023 - academic.oup.com
Background The rationale behind this update of the 2016 British Society for Rheumatology
(BSR) guidelines on prescribing anti-rheumatic drugs in pregnancy and breastfeeding [1, 2] …

Treating systemic lupus erythematosus in the 21st century: new drugs and new perspectives on old drugs

G Ruiz-Irastorza, G Bertsias - Rheumatology, 2020 - academic.oup.com
Besides treating acute flares, the management of SLE should aim at preventing organ
damage accrual and drug-associated harms, improving health-related quality of life and …

[HTML][HTML] Practical guidance for the diagnosis and management of secondary hypogammaglobulinemia: A Work Group Report of the AAAAI Primary Immunodeficiency …

IM Otani, HK Lehman, AM Jongco, LR Tsao… - Journal of Allergy and …, 2022 - Elsevier
Secondary hypogammaglobulinemia (SHG) is characterized by reduced immunoglobulin
levels due to acquired causes of decreased antibody production or increased antibody loss …

[HTML][HTML] An update on the management of childhood-onset systemic lupus erythematosus

VC Trindade, M Carneiro-Sampaio, E Bonfa, CA Silva - Pediatric Drugs, 2021 - Springer
Childhood-onset systemic lupus erythematosus (cSLE) is a prototype of a multisystemic,
inflammatory, heterogeneous autoimmune condition. This disease is characterized by …