[HTML][HTML] Why Do Dietary Flavonoids Have a Promising Effect as Enhancers of Anthracyclines? Hydroxyl Substituents, Bioavailability and Biological Activity
A Golonko, AJ Olichwier, R Swislocka… - International Journal of …, 2022 - mdpi.com
Anthracyclines currently play a key role in the treatment of many cancers, but the limiting
factor of their use is the widespread phenomenon of drug resistance and untargeted toxicity …
factor of their use is the widespread phenomenon of drug resistance and untargeted toxicity …
[HTML][HTML] Flavonoids are intra-and inter-kingdom modulator signals
E Ghitti, E Rolli, E Crotti, S Borin - Microorganisms, 2022 - mdpi.com
Flavonoids are a broad class of secondary metabolites with multifaceted functionalities for
plant homeostasis and are involved in facing both biotic and abiotic stresses to sustain plant …
plant homeostasis and are involved in facing both biotic and abiotic stresses to sustain plant …
Triazole based novel molecules as potential therapeutic agents: Synthesis, characterization, biological evaluation, in-silico ADME profiling and molecular docking …
In this study, eight new compounds (7a-h) based on triazole compounds containing ester
groups were synthesized with high yields. The structures of the synthesized compounds (7a …
groups were synthesized with high yields. The structures of the synthesized compounds (7a …
Synthesis of new thiourea derivatives and metal complexes: Thermal behavior, biological evaluation, in silico ADMET profiling and molecular docking studies
T Yeşilkaynak, FN Özkömeç, M Çeşme… - Journal of Molecular …, 2022 - Elsevier
Abstract In this work, N-((5-bromopyridin-2-yl) carbamothioyl)-2-chlorobenzamide (HL 1)
and N-((5-bromopyridin-2-yl) carbamothioyl) furan-2-carboxamide (HL 2) and its Cu, Ni and …
and N-((5-bromopyridin-2-yl) carbamothioyl) furan-2-carboxamide (HL 2) and its Cu, Ni and …
Novel thiourea derivative compounds: Thermal behavior, biological evaluation, Hirshfeld surfaces and frontier orbitals analyses, in silico ADMET profiling and …
T Yeşilkaynak, FN Özkömeç, M Çeşme… - Journal of Molecular …, 2023 - Elsevier
This work reports synthesis and structural characterization of N-(allylcarbamothioyl)-2-
chlorobenzamide (HL 1, C 11 H 11 ClN 2 OS) and N-(allylcarbamothioyl)-2 …
chlorobenzamide (HL 1, C 11 H 11 ClN 2 OS) and N-(allylcarbamothioyl)-2 …
Inhibition of the predicted allosteric site of the SARS-CoV-2 main protease through flavonoids
Since its emergence in 2019, coronavirus infection (COVID-19) has become a global
pandemic and killed several million people worldwide. Even though several types of …
pandemic and killed several million people worldwide. Even though several types of …
Antioxidant analysis of flavonoids extracted from Artemisia argyi leaf and their antibacterial activities against food-borne pathogens Escherichia coli and …
Z Wang, X Zhou, H Chang, Z Shu, H Gou, Y Zheng… - Biologia, 2024 - Springer
Plant-derived flavonoids have excellent bioactivities and applications, especially those from
herbs, and it is hypothesized that flavonoids also play an important role in the functions of …
herbs, and it is hypothesized that flavonoids also play an important role in the functions of …
[HTML][HTML] Synthesis, structural investigations, and in vitro/in silico bioactivities of flavonoid substituted biguanide: a novel Schiff base and its diorganotin (IV) complexes
Quercetin is one of the most powerful bioactive dietary flavonoids. The in vivo biological
study of quercetin is extremely difficult due to its very low solubility. However, diorganotin …
study of quercetin is extremely difficult due to its very low solubility. However, diorganotin …
[HTML][HTML] Selective structural derivatization of flavonoid acetamides significantly impacts their bioavailability and antioxidant properties
Flavonoids show abundant favorable physicochemical and drug related properties, leading
to substantial biological applications which are limited by undesirable properties such as …
to substantial biological applications which are limited by undesirable properties such as …
[HTML][HTML] Distribution and stability of polyphenols in juices made from traditional apple cultivars grown in Bosnia and Herzegovina
The present research was undertaken to investigate polyphenolic profiles of peel, pulp and
juices made from two standard commercial and five traditional apple cultivars from Bosnia …
juices made from two standard commercial and five traditional apple cultivars from Bosnia …