Microbial Pathway Thermodynamics: Stoichiometric Models Unveil Anabolic and Catabolic Processes

O Ebenhöh, J Ebeling, R Meyer, F Pohlkotte, T Nies - Life, 2024 - mdpi.com
The biotechnological exploitation of microorganisms enables the use of metabolism for the
production of economically valuable substances, such as drugs or food. It is, thus …

A hierarchy of metabolite exchanges in metabolic models of microbial species and communities

YK Wedmark, JO Vik, O Øyås - PLOS Computational Biology, 2024 - journals.plos.org
The metabolic network of an organism can be analyzed as a constraint-based model. This
analysis can be biased, optimizing an objective such as growth rate, or unbiased, aiming to …

Scalable enumeration and sampling of minimal metabolic pathways for organisms and communities

O Øyås, A Theorell, J Stelling - bioRxiv, 2024 - biorxiv.org
Many interactions in microbial consortia or tissues of multicellular organisms rely on
networks of metabolite exchanges. To predict community function and composition beyond …

Microbial pathway thermodynamics: structural models unveil anabolic and catabolic processes

O Ebenhoeh, J Ebeling, R Meyer, F Pohlkotte, T Nies - bioRxiv, 2023 - biorxiv.org
The biotechnological exploitation of microorganisms enables the use of metabolism for the
production of economically valuable substances, such as drugs or food. It is, thus …