Energetics of blood flow in cardiovascular disease: concept and clinical implications of adverse energetics in patients with a Fontan circulation

FM Rijnberg, MG Hazekamp, JJ Wentzel… - Circulation, 2018 - Am Heart Assoc
Visualization and quantification of the adverse effects of distorted blood flow are important
emerging fields in cardiology. Abnormal blood flow patterns can be seen in various …

Fontan surgical planning: previous accomplishments, current challenges, and future directions

PM Trusty, TC Slesnick, ZA Wei, J Rossignac… - Journal of …, 2018 - Springer
The ultimate goal of Fontan surgical planning is to provide additional insights into the clinical
decision-making process. In its current state, surgical planning offers an accurate …

Computational fluid dynamics support for fontan planning in minutes, not hours: the next step in clinical pre-interventional simulations

P Frieberg, N Aristokleous, P Sjöberg, J Töger… - Journal of …, 2022 - Springer
Computational fluid dynamics (CFD) modeling may aid in planning of invasive interventions
in Fontan patients. Clinical application of current CFD techniques is however limited by …

Fluid-structure interaction simulation of an intra-atrial fontan connection

E Tang, Z Wei, MA Fogel, A Veneziani, AP Yoganathan - Biology, 2020 - mdpi.com
Simple Summary A fluid-structure interaction (FSI) simulation of an intra-atrial Fontan
connection was performed. Power loss and pressure drop results fluctuated less during the …

[HTML][HTML] The first cohort of prospective Fontan surgical planning patients with follow-up data: How accurate is surgical planning?

PM Trusty, ZA Wei, TC Slesnick, KR Kanter… - The Journal of thoracic …, 2019 - Elsevier
Objective Fontan surgical planning is an image-based, collaborative effort, which is
hypothesized to result in improved patient outcomes. A common motivation for Fontan …

In vivo hepatic flow distribution by computational fluid dynamics can predict pulmonary flow distribution in patients with Fontan circulation

P Frieberg, P Sjöberg, E Hedström, M Carlsson… - Scientific Reports, 2023 - nature.com
In Fontan patients, a lung deprived of hepatic blood may develop pulmonary arterio-venous
malformations (PAVMs) resulting in shunting, reduced pulmonary vascular resistance (PVR) …

Effect of Fontan geometry on exercise haemodynamics and its potential implications

E Tang, ZA Wei, KK Whitehead, RH Khiabani… - Heart, 2017 - heart.bmj.com
Objective Exercise intolerance afflicts Fontan patients with total cavopulmonary connections
(TCPCs) causing a reduction in quality of life. Optimising TCPC design is hypothesised to …

Non-Newtonian effects on patient-specific modeling of Fontan hemodynamics

Z Wei, S Singh-Gryzbon, PM Trusty… - Annals of biomedical …, 2020 - Springer
The Fontan procedure is a common palliative surgery for congenital single ventricle patients.
In silico and in vitro patient-specific modeling approaches are widely utilized to investigate …

Analysis of inlet velocity profiles in numerical assessment of Fontan hemodynamics

ZA Wei, C Huddleston, PM Trusty… - Annals of biomedical …, 2019 - Springer
Computational fluid dynamic (CFD) simulations are widely utilized to assess Fontan
hemodynamics that are related to long-term complications. No previous studies have …

The advantages of viscous dissipation rate over simplified power loss as a Fontan hemodynamic metric

ZA Wei, M Tree, PM Trusty, W Wu… - Annals of biomedical …, 2018 - Springer
Flow efficiency through the Fontan connection is an important factor related to patient
outcomes. It can be quantified using either a simplified power loss or a viscous dissipation …