Genomics, convergent neuroscience and progress in understanding autism spectrum disorder
More than a hundred genes have been identified that, when disrupted, impart large risk for
autism spectrum disorder (ASD). Current knowledge about the encoded proteins—although …
autism spectrum disorder (ASD). Current knowledge about the encoded proteins—although …
[HTML][HTML] Can the “female protective effect” liability threshold model explain sex differences in autism spectrum disorder?
Male sex is a strong risk factor for autism spectrum disorder (ASD). The leading theory for a"
female protective effect"(FPE) envisions males and females have" differing thresholds" …
female protective effect"(FPE) envisions males and females have" differing thresholds" …
[HTML][HTML] The female protective effect against autism spectrum disorder
Autism spectrum disorder (ASD) is diagnosed three to four times more frequently in males
than in females. Genetic studies of rare variants support a female protective effect (FPE) …
than in females. Genetic studies of rare variants support a female protective effect (FPE) …
[HTML][HTML] Rare X-linked variants carry predominantly male risk in autism, Tourette syndrome, and ADHD
Autism spectrum disorder (ASD), Tourette syndrome (TS), and attention-deficit/hyperactivity
disorder (ADHD) display strong male sex bias, due to a combination of genetic and …
disorder (ADHD) display strong male sex bias, due to a combination of genetic and …
Clinical and translational implications of an emerging developmental substructure for autism
JN Constantino, T Charman… - Annual review of clinical …, 2021 - annualreviews.org
A vast share of the population-attributable risk for autism relates to inherited polygenic risk. A
growing number of studies in the past five years have indicated that inherited susceptibility …
growing number of studies in the past five years have indicated that inherited susceptibility …
[HTML][HTML] Infant feeding practices and autism spectrum disorder in US children aged 2–5 years: the national survey of children's health (NSCH) 2016–2020
Objective To investigate the relationship between infant feeding practices and autism
spectrum disorder (ASD) among children aged 2–5 years in the United States (US). Methods …
spectrum disorder (ASD) among children aged 2–5 years in the United States (US). Methods …
Examining sex differences in autism heritability
Importance Autism spectrum disorder (ASD) is a neurodevelopmental disorder more
prevalent in males than in females. The cause of ASD is largely genetic, but the association …
prevalent in males than in females. The cause of ASD is largely genetic, but the association …
Emotion processing differences mediate the link between sex and autistic traits in young adulthood
Background The male preponderance in autism diagnoses is widely reported, yet the
psychological mechanisms (eg, emotion processing) underlying this sex difference are …
psychological mechanisms (eg, emotion processing) underlying this sex difference are …
Autism spectrum disorder
MO Bertelli, MW Azeem, L Underwood… - Textbook of psychiatry …, 2022 - Springer
Autism spectrum disorder (ASD) represents a highly heterogeneous group of
neurodevelopmental conditions with early-onset impairments in social communication and …
neurodevelopmental conditions with early-onset impairments in social communication and …
Facial asymmetry in parents of children on the autism spectrum
Greater facial asymmetry has been consistently found in children with autism spectrum
disorder (ASD) relative to children without ASD. There is substantial evidence that both …
disorder (ASD) relative to children without ASD. There is substantial evidence that both …