Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria
Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …
accounting for the majority of malaria, and P. vivax being a second important cause …
Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination
T Bousema, C Drakeley - Clinical microbiology reviews, 2011 - Am Soc Microbiol
Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …
falciparum responsible for the majority of the disease burden and P. vivax being the …
Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing
Malaria elimination strategies require surveillance of the parasite population for genetic
changes that demand a public health response, such as new forms of drug resistance,. Here …
changes that demand a public health response, such as new forms of drug resistance,. Here …
Plasmodium Genomics and Genetics: New Insights into Malaria Pathogenesis, Drug Resistance, Epidemiology, and Evolution
Protozoan Plasmodium parasites are the causative agents of malaria, a deadly disease that
continues to afflict hundreds of millions of people every year. Infections with malaria …
continues to afflict hundreds of millions of people every year. Infections with malaria …
The Plasmodium bottleneck: malaria parasite losses in the mosquito vector
RC Smith, J Vega-Rodríguez… - Memórias do Instituto …, 2014 - SciELO Brasil
Nearly one million people are killed every year by the malaria parasite Plasmodium.
Although the disease-causing forms of the parasite exist only in the human blood …
Although the disease-causing forms of the parasite exist only in the human blood …
Challenges and strategies for developing efficacious and long-lasting malaria vaccines
Although there has been major recent progress in malaria vaccine development, substantial
challenges remain for achieving highly efficacious and durable vaccines against …
challenges remain for achieving highly efficacious and durable vaccines against …
Malaria parasite liver infection and exoerythrocytic biology
AM Vaughan, SHI Kappe - Cold Spring …, 2017 - perspectivesinmedicine.cshlp.org
In their infection cycle, malaria parasites undergo replication and population expansions
within the vertebrate host and the mosquito vector. Host infection initiates with sporozoite …
within the vertebrate host and the mosquito vector. Host infection initiates with sporozoite …
Generating conditional gene knockouts in Plasmodium – a toolkit to produce stable DiCre recombinase-expressing parasite lines using CRISPR/Cas9
Successful establishment of CRISPR/Cas9 genome editing technology in Plasmodium spp.
has provided a powerful tool to transform Plasmodium falciparum into a genetically more …
has provided a powerful tool to transform Plasmodium falciparum into a genetically more …
Identification of genes required for Plasmodium gametocyte-to-sporozoite development in the mosquito vector
Malaria remains one of the most devastating infectious diseases. Reverse genetic screens
offer a powerful approach to identify genes and molecular processes governing malaria …
offer a powerful approach to identify genes and molecular processes governing malaria …
Transmission-blocking vaccines: harnessing herd immunity for malaria elimination
PE Duffy - Expert Review of Vaccines, 2021 - Taylor & Francis
Introduction Transmission-blocking vaccines (TBV) prevent community spread of malaria by
targeting mosquito sexual stage parasites, a life-cycle bottleneck, and will be used in …
targeting mosquito sexual stage parasites, a life-cycle bottleneck, and will be used in …