European academy of neurology/Movement Disorder Society‐European section guideline on the treatment of Parkinson's disease: I. Invasive therapies

G Deuschl, A Antonini, J Costa… - European Journal of …, 2022 - Wiley Online Library
Abstract Background and Purpose This update of the treatment guidelines was
commissioned by the European Academy of Neurology and the European section of the …

How does deep brain stimulation change the course of Parkinson's disease?

P Mahlknecht, T Foltynie, P Limousin… - Movement …, 2022 - Wiley Online Library
A robust body of evidence from randomized controlled trials has established the efficacy of
deep brain stimulation (DBS) in reducing off time and dyskinesias in levodopa‐treated …

Medical, surgical, and physical treatments for Parkinson's disease

T Foltynie, V Bruno, S Fox, AA Kühn, F Lindop, AJ Lees - The Lancet, 2024 - thelancet.com
Although dopamine replacement therapy remains a core component of Parkinson's disease
treatment, the onset of motor fluctuations and dyskinetic movements might require a range of …

[HTML][HTML] From prodromal stages to clinical trials: The promise of digital speech biomarkers in Parkinson's disease

J Rusz, P Krack, E Tripoliti - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
Speech impairment is a common and disabling symptom in Parkinson's disease (PD),
affecting communication and quality of life. Advances in digital speech processing and …

The role of levodopa challenge in predicting the outcome of subthalamic deep brain stimulation

R Wolke, JS Becktepe, S Paschen… - Movement disorders …, 2023 - Wiley Online Library
Background Deep brain stimulation of the subthalamic nucleus (STN‐DBS) is an effective
and evidence‐based treatment for idiopathic Parkinson's disease (iPD). A minority of …

At home adaptive dual target deep brain stimulation in Parkinson's disease with proportional control

SL Schmidt, AH Chowdhury, KT Mitchell, JJ Peters… - Brain, 2024 - academic.oup.com
Continuous deep brain stimulation (cDBS) of the subthalamic nucleus (STN) or globus
pallidus is an effective treatment for the motor symptoms of Parkinson's disease. The relative …

Advances in DBS technology and novel applications: focus on movement disorders

SR Potel, S Marceglia, S Meoni, SK Kalia… - Current Neurology and …, 2022 - Springer
Abstract Purpose of Review Deep brain stimulation (DBS) is an established treatment in
several movement disorders, including Parkinson's disease, dystonia, tremor, and Tourette …

Pathological pain: non-motor manifestations in Parkinson disease and its treatment.

J Lei, LL Tang, HJ You - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
In addition to motor symptoms, non-motor manifestations of Parkinson's disease (PD), ie
pain, depression, sleep disturbance, and autonomic disorders, have received increasing …

Deep brain stimulation in Parkinson's disease: state of the art and future perspectives

C França, RB Carra, JM Diniz, RP Munhoz… - Arquivos de Neuro …, 2022 - SciELO Brasil
For more than 30 years, Deep Brain Stimulation (DBS) has been a therapeutic option for
Parkinson's disease (PD) treatment. However, this therapy is still underutilized mainly due to …

Differential Cognitive Effects of Unilateral Subthalamic Nucleus Deep Brain Stimulation for Parkinson's Disease

VA Del Bene, RC Martin, SA Brinkerhoff… - Annals of …, 2024 - Wiley Online Library
Objective The aim of this study was to investigate the cognitive effects of unilateral
directional versus ring subthalamic nucleus deep brain stimulation (STN DBS) in patients …