Para-hydrogen perspectives in hyperpolarized NMR

S Glöggler, J Colell, S Appelt - Journal of Magnetic Resonance, 2013 - Elsevier
The first instance of para-hydrogen induced polarization (PHIP) in an NMR experiment was
serendipitously observed in the 1980s while investigating a hydrogenation reaction (Seldler …

The role of level anti-crossings in nuclear spin hyperpolarization

KL Ivanov, AN Pravdivtsev, AV Yurkovskaya… - Progress in nuclear …, 2014 - Elsevier
Nuclear spin hyperpolarization is an important resource for increasing the sensitivity of NMR
spectroscopy and MRI. Signal enhancements can be as large as 3–4 orders of magnitude …

High-Pressure Clinical-Scale 87% Parahydrogen Generator

JR Birchall, AM Coffey, BM Goodson… - Analytical …, 2020 - ACS Publications
We present an automated parahydrogen generator (ParaSun) for clinical-scale applications
in parahydrogen-induced polarization (PHIP) and signal amplification by reversible …

2D mapping of NMR signal enhancement and relaxation for heterogeneously hyperpolarized propane gas

DA Barskiy, KV Kovtunov, EY Gerasimov… - The Journal of …, 2017 - ACS Publications
Hyperpolarized (HP) propane is a promising contrast agent for magnetic resonance imaging
(MRI) of lungs and for studying porous media. The parahydrogen-induced polarization …

Manipulating spin hyper-polarization by means of adiabatic switching of a spin-locking RF-field

AS Kiryutin, KL Ivanov, AV Yurkovskaya… - Physical Chemistry …, 2013 - pubs.rsc.org
We propose a technique for transferring the multiplet spin polarization (CIDNP or PHIP, or
one created by any other method), which is the mutual entanglement of spins, into net hyper …

Exploiting adiabatically switched RF-field for manipulating spin hyperpolarization induced by parahydrogen

AS Kiryutin, AV Yurkovskaya, NN Lukzen… - The Journal of …, 2015 - pubs.aip.org
A method for precise manipulation of non-thermal nuclear spin polarization by switching a
RF-field is presented. The method harnesses adiabatic correlation of spin states in the …

New pulse sequence for robust filtering of hyperpolarized multiplet spin order

AN Pravdivtsev, KL Ivanov, AV Yurkovskaya… - Doklady Physical …, 2015 - Springer
Abstract A new Nuclear Magnetic Resonance (NMR) pulse sequence is proposed for
manipulating ParaHydrogen Induced Polarization (PHIP) at high magnetic fields. The …

Single-Shot MRI in parahydrogen hyperpolarized samples

L Buljubasich - Journal of Magnetic Resonance, 2024 - Elsevier
The site-specific signal enhancement provided by parahydrogen induced polarization
(PHIP) may be combined with magnetic resonance imaging (MRI) to study chemical and …

Diffusion measurements with continuous hydrogenation in PHIP

S Bussandri, L Buljubasich, RH Acosta - Journal of Magnetic Resonance, 2020 - Elsevier
DOSY is a powerful spectroscopic NMR technique that resolves components in mixtures
through the evaluation of different diffusion coefficients. The application of DOSY to dilute …

High resolution NMR study of T1 magnetic relaxation dispersion. IV. Proton relaxation in amino acids and Met-enkephalin pentapeptide

AN Pravdivtsev, AV Yurkovskaya, HM Vieth… - The Journal of chemical …, 2014 - pubs.aip.org
High resolution NMR study of T1 magnetic relaxation dispersion. IV. Proton relaxation in amino
acids and Met-enkephalin pentapeptide | The Journal of Chemical Physics | AIP Publishing Skip …