[HTML][HTML] The roles of TGF-β and VEGF pathways in the suppression of antitumor immunity in melanoma and other solid tumors

MT Bu, P Chandrasekhar, L Ding, W Hugo - Pharmacology & therapeutics, 2022 - Elsevier
Immune checkpoint blockade (ICB) has become well-known in cancer therapy,
strengthening the body's antitumor immune response rather than directly targeting cancer …

Predictive biomarkers for immunotherapy in gastric cancer: current status and emerging prospects

W Hou, Y Zhao, H Zhu - International Journal of Molecular Sciences, 2023 - mdpi.com
Gastric cancer presents substantial management challenges, and the advent of
immunotherapy has ignited renewed hope among patients. Nevertheless, a significant …

Augmenting Immunotherapy via Bioinspired MOF‐Based ROS Homeostasis Disruptor with Nanozyme‐Cascade Reaction

R Wang, M Qiu, L Zhang, M Sui, L Xiao, Q Yu… - Advanced …, 2023 - Wiley Online Library
Despite its remarkable clinical breakthroughs, immune checkpoint blockade (ICB) therapy
remains limited by the insufficient immune response in the “cold” tumor. Nanozyme‐based …

Immune infiltration and clinical significance analyses of the coagulation-related genes in hepatocellular carcinoma

Q He, J Yang, Y Jin - Briefings in bioinformatics, 2022 - academic.oup.com
Hepatocellular carcinoma (HCC) is one of the most common types of cancers and a global
health challenge with a low early diagnosis rate and high mortality. The coagulation …

Association of tumor mutational burden with efficacy of pembrolizumab±chemotherapy as first-line therapy for gastric cancer in the phase III KEYNOTE-062 study

KW Lee, E Van Cutsem, YJ Bang, CS Fuchs… - Clinical Cancer …, 2022 - AACR
Purpose: This prespecified exploratory analysis evaluated the association between tumor
mutational burden (TMB) status and outcomes of first-line pembrolizumab {plus minus} …

Comprehensive assessment of immune context and immunotherapy response via noninvasive imaging in gastric cancer

Z Sun, T Zhang, MU Ahmad, Z Zhou… - The Journal of …, 2024 - Am Soc Clin Investig
BACKGROUND The tumor immune microenvironment can provide prognostic and
therapeutic information. We aimed to develop noninvasive imaging biomarkers from …

MFSD2A potentiates gastric cancer response to anti‐PD‐1 immunotherapy by reprogramming the tumor microenvironment to activate T cell response

B Zhang, CM Wang, HX Wu, F Wang… - Cancer …, 2023 - Wiley Online Library
Background The efficacy of anti‐programmed cell death protein 1 (PD‐1) immunotherapy in
various cancers, including gastric cancer (GC), needs to be potentiated by more effective …

Immune checkpoint inhibitors promising role in cancer therapy: Clinical evidence and immune-related adverse events

SM Meybodi, B Farasati Far, A Pourmolaei… - Medical Oncology, 2023 - Springer
The advent of immune checkpoint inhibitors (ICIs) has led to noteworthy progressions in the
management of diverse cancer types, as evidenced by the pioneering “ipilimumab” …

A novel m7G regulator‐based methylation patterns in head and neck squamous cell carcinoma

Y Ying, W Zhang, H Zhu, J Luo, X Xu… - Molecular …, 2023 - Wiley Online Library
Abnormal RNA N7‐methylguanosine (m7G) modification is known to contribute to effects on
tumor occurrence and development. Nevertheless, the mechanisms of its function in …

Visual analysis of global research on immunotherapy for gastric cancer: a literature mining from 2012 to 2022

Y Chen, Y Chen, S Tan, Y Zheng, S Liu… - Human Vaccines & …, 2023 - Taylor & Francis
Gastric cancer (GC) is one of the most common malignancies. Immunotherapy becomes an
indispensable part of GC. This study conducts bibliometric analysis of immunotherapy for …