[HTML][HTML] Pancreatic β-cell proliferation in obesity
AK Linnemann, M Baan, DB Davis - Advances in nutrition, 2014 - Elsevier
Because obesity rates have increased dramatically over the past 3 decades, type 2 diabetes
has become increasingly prevalent as well. Type 2 diabetes is associated with decreased …
has become increasingly prevalent as well. Type 2 diabetes is associated with decreased …
[HTML][HTML] Host genetic factors affecting hepatitis B infection outcomes: Insights from genome-wide association studies
IM Akcay, S Katrinli, K Ozdil, GD Doganay… - World journal of …, 2018 - ncbi.nlm.nih.gov
The clinical outcome of hepatitis B virus (HBV) infection depends on the success or failure of
the immune responses to HBV, and varies widely among individuals, ranging from …
the immune responses to HBV, and varies widely among individuals, ranging from …
Circ-ZNF609 regulates G1-S progression in rhabdomyosarcoma
Circular RNAs (circRNAs) represent a class of covalently closed RNAs, derived from non-
canonical splicing events, which are expressed in all eukaryotes and often conserved …
canonical splicing events, which are expressed in all eukaryotes and often conserved …
Co‐targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor‐resistant melanoma
IM Echevarría‐Vargas, PI Reyes‐Uribe… - EMBO molecular …, 2018 - embopress.org
Despite novel therapies for melanoma, drug resistance remains a significant hurdle to
achieving optimal responses. NRAS‐mutant melanoma is an archetype of therapeutic …
achieving optimal responses. NRAS‐mutant melanoma is an archetype of therapeutic …
[HTML][HTML] COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types
BJ Schmiedel, J Rocha, C Gonzalez-Colin… - Nature …, 2021 - nature.com
Common genetic polymorphisms associated with COVID-19 illness can be utilized for
discovering molecular pathways and cell types driving disease pathogenesis. Given the …
discovering molecular pathways and cell types driving disease pathogenesis. Given the …
[HTML][HTML] Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion
FK Ndiaye, A Ortalli, M Canouil, M Huyvaert… - Molecular …, 2017 - Elsevier
Objectives Genome-wide association studies (GWAS) have identified> 100 loci
independently contributing to type 2 diabetes (T2D) risk. However, translational implications …
independently contributing to type 2 diabetes (T2D) risk. However, translational implications …
Autophagy stimulation abrogates herpes simplex virus-1 infection
AM Yakoub, D Shukla - Scientific Reports, 2015 - nature.com
Abstract Herpes simplex virus-1 (HSV-1) is a double-stranded DNA virus that causes life-
long infections. HSV-1 infections may lead to herpetic stromal keratitis that may advance to …
long infections. HSV-1 infections may lead to herpetic stromal keratitis that may advance to …
TCF19 promotes cell proliferation through binding to the histone H3K4me3 mark
Transcription factor 19 (TCF19) plays critical roles in type 1 diabetes and the maintenance of
pancreatic β cells. Recent studies have also implicated TCF19 in cell proliferation of hepatic …
pancreatic β cells. Recent studies have also implicated TCF19 in cell proliferation of hepatic …
TCF19 and p53 regulate transcription of TIGAR and SCO2 in HCC for mitochondrial energy metabolism and stress adaptation
Alteration in glucose homeostasis during cancer metabolism is an important phenomenon.
Though several important transcription factors have been well studied in the context of the …
Though several important transcription factors have been well studied in the context of the …
[HTML][HTML] Clinical and Immunohistochemical epithelial profile of non-healing chronic traumatic ulcers
GM Gilligan, RL Panico, C Di Tada… - … Oral, Patología Oral y …, 2020 - ncbi.nlm.nih.gov
Background Chronic wounds were previously related to cancer. Chronic Traumatic Ulcers
(CTU) are lesions caused by chronic mechanical irritation (CMI) frequently diagnosed in …
(CTU) are lesions caused by chronic mechanical irritation (CMI) frequently diagnosed in …