Functional probes for the diagnosis and treatment of infectious diseases
Infectious diseases present significant challenges to global health, thereby extensively
affecting both human society and the economy. In recent years, functional probes have …
affecting both human society and the economy. In recent years, functional probes have …
Nanotechnology in healthcare, and its safety and environmental risks
X Ma, Y Tian, R Yang, H Wang, LW Allahou… - Journal of …, 2024 - Springer
Nanotechnology holds immense promise in revolutionising healthcare, offering
unprecedented opportunities in diagnostics, drug delivery, cancer therapy, and combating …
unprecedented opportunities in diagnostics, drug delivery, cancer therapy, and combating …
Engineered Probiotic Bio‐Heterojunction with Robust Antibiofilm Modality via “Eating” Extracellular Polymeric Substances for Wound Regeneration
M Qin, X Zhang, H Ding, Y Chen, W He… - Advanced …, 2024 - Wiley Online Library
The compact three‐dimensional (3D) structure of extracellular polymeric substances (EPS)
within biofilms significantly hinders the penetration of antimicrobial agents, making biofilm …
within biofilms significantly hinders the penetration of antimicrobial agents, making biofilm …
Reaction‐Induced Self‐Assembly of Polymyxin Mitigates Cytotoxicity and Reverses Drug Resistance
Polymyxins have been regarded as an efficient therapeutic against many life‐threatening,
multidrug resistant Gram‐negative bacterial infections; however, the cytotoxicity and …
multidrug resistant Gram‐negative bacterial infections; however, the cytotoxicity and …
Type I Photosensitizer Targeting Glycans: Overcoming Biofilm Resistance by Inhibiting the Two‐Component System, Quorum Sensing, and Multidrug Efflux
FW Xia, BW Guo, Y Zhao, JL Wang, Y Chen… - Advanced …, 2023 - Wiley Online Library
Stubborn biofilm infections pose serious threats to human health due to the persistence,
recurrence, and dramatically magnified antibiotic resistance. Photodynamic therapy has …
recurrence, and dramatically magnified antibiotic resistance. Photodynamic therapy has …
Key progresses of MOE key laboratory of macromolecular synthesis and functionalization in 2023
Abstract In 2023, The MOE Key Laboratory of Macromolecular Synthesis and
Functionalization in Zhejiang University had achieved several important results in the five …
Functionalization in Zhejiang University had achieved several important results in the five …
The Art of War with Pseudomonas aeruginosa: Targeting Mex Efflux Pumps Directly to Strategically Enhance Antipseudomonal Drug Efficacy
Pseudomonas aeruginosa (P. aeruginosa) poses a grave clinical challenge due to its
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …
Microwave‐Responsive Nanoplatform with Robust ROS Generation and Inhibiting Effects of Two‐Component System and Quorum Sensing for the Treatment of MRSA …
H Cheng, Y Yang, Y Wang, J Guo… - Advanced Functional …, 2024 - Wiley Online Library
The hypoxic environment of deep tissue and the weak energy of microwave (MW) are still
the major limitations of MW catalytic therapy. In this work, an MW‐responsive nano‐platform …
the major limitations of MW catalytic therapy. In this work, an MW‐responsive nano‐platform …
Poly(d-amino acid) Nanoparticles Target Staphylococcal Growth and Biofilm Disassembly by Interfering with Peptidoglycan Synthesis
d-Amino acids are signals for biofilm disassembly. However, unexpected metabolic
pathways severely attenuate the utilization of d-amino acids in biofilm disassembly, resulting …
pathways severely attenuate the utilization of d-amino acids in biofilm disassembly, resulting …
Polyzwitterionic micelles with antimicrobial-conjugation for eradication of drug-resistant bacterial biofilms
The presence of bacterial biofilms has presented a significant challenge to human health.
This study presents the development of biofilm microenvironment-responsive polymeric …
This study presents the development of biofilm microenvironment-responsive polymeric …