Tumour-associated neutrophils in patients with cancer
ME Shaul, ZG Fridlender - Nature reviews Clinical oncology, 2019 - nature.com
The role and importance of neutrophils in cancer has become increasingly apparent over
the past decade. Neutrophils accumulate in the peripheral blood of patients with cancer …
the past decade. Neutrophils accumulate in the peripheral blood of patients with cancer …
Cancer‐related circulating and tumor‐associated neutrophils–subtypes, sources and function
ME Shaul, ZG Fridlender - The FEBS journal, 2018 - Wiley Online Library
In recent years, the role of neutrophils in cancer biology has been a matter of increasing
interest. Many patients with advanced cancer show high levels of neutrophilia, tumor …
interest. Many patients with advanced cancer show high levels of neutrophilia, tumor …
EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure
The term acute liver failure (ALF) is frequently applied as a generic expression to describe
patients presenting with or developing an acute episode of liver dysfunction. In the context of …
patients presenting with or developing an acute episode of liver dysfunction. In the context of …
Oxidized phospholipids on lipoprotein (a) elicit arterial wall inflammation and an inflammatory monocyte response in humans
Background: Elevated lipoprotein (a)[Lp (a)] is a prevalent, independent cardiovascular risk
factor, but the underlying mechanisms responsible for its pathogenicity are poorly defined …
factor, but the underlying mechanisms responsible for its pathogenicity are poorly defined …
Myocardial and systemic inflammation in acute stress-induced (Takotsubo) cardiomyopathy
C Scally, H Abbas, T Ahearn, J Srinivasan… - Circulation, 2019 - Am Heart Assoc
Background: Acute stress-induced (takotsubo) cardiomyopathy can result in a heart failure
phenotype with a prognosis comparable with that of myocardial infarction. In this study, we …
phenotype with a prognosis comparable with that of myocardial infarction. In this study, we …
Dictys: dynamic gene regulatory network dissects developmental continuum with single-cell multiomics
L Wang, N Trasanidis, T Wu, G Dong, M Hu… - Nature …, 2023 - nature.com
Gene regulatory networks (GRNs) are key determinants of cell function and identity and are
dynamically rewired during development and disease. Despite decades of advancement …
dynamically rewired during development and disease. Despite decades of advancement …
Bone marrow mesenchymal stromal cell treatment in patients with osteoarthritis results in overall improvement in pain and symptoms and reduces synovial …
J Chahal, A Gómez-Aristizábal… - Stem cells …, 2019 - academic.oup.com
Patients with late-stage Kellgren-Lawrence knee osteoarthritis received a single intra-
articular injection of 1, 10, or 50 million bone marrow mesenchymal stromal cells (BM-MSCs) …
articular injection of 1, 10, or 50 million bone marrow mesenchymal stromal cells (BM-MSCs) …
PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia
Aims Migration of monocytes into the arterial wall contributes to arterial inflammation and
atherosclerosis progression. Since elevated low-density lipoprotein cholesterol (LDL-C) …
atherosclerosis progression. Since elevated low-density lipoprotein cholesterol (LDL-C) …
Clinical significance of monocyte heterogeneity
BK Stansfield, DA Ingram - Clinical and translational medicine, 2015 - Springer
Monocytes are primitive hematopoietic cells that primarily arise from the bone marrow,
circulate in the peripheral blood and give rise to differentiated macrophages. Over the past …
circulate in the peripheral blood and give rise to differentiated macrophages. Over the past …
MicroRNA: dynamic regulators of macrophage polarization and plasticity
JB Self-Fordham, AR Naqvi, JR Uttamani… - Frontiers in …, 2017 - frontiersin.org
The ability of a healthy immune system to clear the plethora of antigens it encounters
incessantly relies on the enormous plasticity displayed by the comprising cell types …
incessantly relies on the enormous plasticity displayed by the comprising cell types …