Abstract Purpose of Review Atherosclerosis is now considered a chronic inflammatory
disease. Oxidative stress induced by generation of excess reactive oxygen species has …

Major reactive oxygen species (ROS)–producing systems in vascular wall include NADPH
(reduced form of nicotinamide adenine dinucleotide phosphate) oxidase, xanthine oxidase …

Vascular disease and heart failure impart an enormous burden in terms of global morbidity
and mortality. Although there are many different causes of cardiac and vascular disease …

Resveratrol increases the production of nitric oxide (NO) in endothelial cells by upregulating
the expression of endothelial NO synthase (eNOS), stimulating eNOS enzymatic activity, and …

The antioxidant effects of resveratrol (3, 5, 4'‐trihydroxy‐trans‐stilbene) contribute
substantially to the health benefits of this compound. Resveratrol has been shown to be a …

Resveratrol, a natural polyphenolic compound, is found in various kinds of fruits, plants, and
their commercial products such as red wine. It has been demonstrated to exhibit a variety of …

In the vascular wall, reactive oxygen species (ROS) are produced by several enzyme
systems including NADPH oxidase, xanthine oxidase, uncoupled endothelial nitric oxide …

Over the last decade, a dual character of cell response to oxidative stress, eustress versus
distress, has become increasingly recognized. A growing body of evidence indicates that …

Diabetes is a disease that can be treated with oral antidiabetic agents and/or insulin.
However, patients' metabolic control is inadequate in a high percentage of them and a major …

Nitric oxide (radical dot NO) is synthetized enzymatically from l-arginine (l-Arg) by three NO
synthase isoforms, iNOS, eNOS and nNOS. The synthesis of NO is selectively inhibited by …