The role of m6A RNA methylation in cancer: implication for nature products anti-cancer research

N Song, K Cui, K Zhang, J Yang, J Liu, Z Miao… - Frontiers in …, 2022 - frontiersin.org
N6-methyladenosine (m6A) RNA methylation is identified as the most common, abundant
and reversible RNA epigenetic modification in messenger RNA (mRNA) and non-coding …

Opuntia ficus-indica (L.) Mill. - anticancer properties and phytochemicals: current trends and future perspectives

J Wang, N Rani, S Jakhar, R Redhu, S Kumar… - Frontiers in Plant …, 2023 - frontiersin.org
Cancer is a leading cause of mortality worldwide, and conventional cancer therapies such
as chemotherapy and radiotherapy often result in undesirable and adverse effects. Natural …

[HTML][HTML] The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through# INPST hashtag analysis

RK Singla, R De, T Efferth, B Mezzetti, MS Uddin… - Phytomedicine, 2023 - Elsevier
Background The development of digital technologies and the evolution of open innovation
approaches have enabled the creation of diverse virtual organizations and enterprises …

Natural products derived from medicinal plants and microbes might act as a game-changer in breast cancer: A comprehensive review of preclinical and clinical studies

RK Singla, X Wang, R Gundamaraju… - Critical Reviews in …, 2023 - Taylor & Francis
Breast cancer (BC) is the most prevalent neoplasm among women. Genetic and
environmental factors lead to BC development and on this basis, several preventive …

Synergistic effects of natural products in combination with anticancer agents in prostate cancer: A scoping review

C Cheon, SG Ko - Frontiers in pharmacology, 2022 - frontiersin.org
Background: Prostate cancer is the second most common cancer in men and has the fourth
highest mortality among men worldwide. Different combination therapies for cancer are …

Current trends in natural products for the treatment and management of dementia: Computational to clinical studies

RK Singla, S Joon, B Sinha, MA Kamal… - Neuroscience & …, 2023 - Elsevier
The number of preclinical and clinical studies evaluating natural products-based
management of dementia has gradually increased, with an exponential rise in 2020 and …

Biosynthesis of anticancer phytochemical compounds and their chemistry

A Dogra, J Kumar - Frontiers in Pharmacology, 2023 - frontiersin.org
Cancer is a severe health issue, and cancer cases are rising yearly. New anticancer drugs
have been developed as our understanding of the molecular mechanisms behind diverse …

Unraveling the peculiar features of mitochondrial metabolism and dynamics in prostate cancer

F Fontana, M Anselmi, P Limonta - Cancers, 2023 - mdpi.com
Simple Summary Mitochondria are organelles involved in different biological processes,
including tumorigenesis. Accumulating evidence strongly supports that, despite the …

Lycopene enhances the sensitivity of castration-resistant prostate cancer to enzalutamide through the AKT/EZH2/androgen receptor signaling pathway

X Chen, G Yang, M Liu, Z Quan, L Wang, C Luo… - Biochemical and …, 2022 - Elsevier
Enzalutamide is an effective drug for the treatment of castration-resistant prostate cancer
(CRPC), but acquired enzalutamide resistance is usually unavoidable within the short term …

Natural kinase inhibitors for the treatment and management of endometrial/uterine cancer: preclinical to clinical studies

RK Singla, S Behzad, J Khan, C Tsagkaris… - Frontiers in …, 2022 - frontiersin.org
Endometrial cancer (EC) is the sixth most prevalent type of cancer among women. Kinases,
enzymes mediating the transfer of adenosine triphosphate (ATP) in several signaling …