In asthma and allergy genetics, a trend towards a few main topics developed over the last 2
years. First, a number of studies have been published recently which focus on overlapping …

Current management of severe asthma relying either on guidelines (bulk approach) or on
disease phenotypes (stratified approach) did not improve the burden of the disease. Several …

Background The mast cell-specific metalloprotease CPA3 has been given important roles in
lung tissue homeostasis and disease pathogenesis. However, the dynamics and spatial …

Background Mast cells (MCs) and basophils are important in asthma pathophysiology,
however direct measurement is difficult, and clinical and inflammatory associations in severe …

Introduction Asthma is one of the most frequent chronic diseases all over the world.
Glucocorticoids (GCs), both inhaled (ICSs) and oral (OCSs), are the most effective treatment …

Chronic airflow obstruction affects a wide range of airway diseases, the most frequent of
which are asthma, COPD, and bronchiectasis; they are clearly identifiable in their extremes …

Eosinophils have multiple relevant biological functions, including the maintenance of
homeostasis, host defense against infectious agents, innate immunity activities, immune …

Information for Category 1 CME Credit Credit can now be obtained, free for a limited time, by
reading the review articles in this issue. Please note the following instructions. Method of …

While the origin of the phrase “birds of a feather flock together” is unclear, it has been in use
for centuries and is typically employed to describe the phenomenon that people with similar …

Background Liquid biomarkers have shown increasing utility in the clinical management of
airway diseases. Salivary and blood samples are particularly amenable to point-of-care …