Fast inference of genetic recombination rates in biobank scale data
Although rates of recombination events across the genome (genetic maps) are fundamental
to genetic research, the majority of current studies only use one standard map. There is …
to genetic research, the majority of current studies only use one standard map. There is …
Haplotype threading using the positional Burrows-Wheeler transform
In the classic model of population genetics, one haplotype (query) is considered as a mosaic
copy of segments from a number of haplotypes in a panel, or threading the haplotype …
copy of segments from a number of haplotypes in a panel, or threading the haplotype …
FastRecomb: Fast inference of genetic recombination rates in biobank scale data
A genetic map for a population or a species contains the locations of genetic markers or
variant sites in relation to one another based on the probability of recombination, rather than …
variant sites in relation to one another based on the probability of recombination, rather than …
Minimal positional substring cover is a haplotype threading alternative to Li and Stephens model
The Li and Stephens (LS) hidden Markov model (HMM) models the process of
reconstructing a haplotype as a mosaic copy of haplotypes in a reference panel. For small …
reconstructing a haplotype as a mosaic copy of haplotypes in a reference panel. For small …