Melanoma and microbiota: Current understanding and future directions

B Routy, T Jackson, L Mählmann, CK Baumgartner… - Cancer cell, 2024 - cell.com
Over the last decade, the composition of the gut microbiota has been found to correlate with
the outcomes of cancer patients treated with immunotherapy. Accumulating evidence points …

Host–pathobiont interactions in Crohn's disease

R Caruso, BC Lo, GY Chen, G Núñez - … Reviews Gastroenterology & …, 2024 - nature.com
The mammalian intestine is colonized by trillions of microorganisms that are collectively
referred to as the gut microbiota. The majority of symbionts have co-evolved with their host in …

Secreted antigen A peptidoglycan hydrolase is essential for Enterococcus faecium cell separation and priming of immune checkpoint inhibitor therapy

S Klupt, KT Fam, X Zhang, PK Chodisetti, A Mehmood… - Elife, 2024 - elifesciences.org
Enterococcus faecium is a microbiota species in humans that can modulate host immunity
(Griffin and Hang, 2022), but has also acquired antibiotic resistance and is a major cause of …

Bicarbonate secretion and acid/base sensing by the intestine

HM Becker, UE Seidler - Pflügers Archiv-European Journal of Physiology, 2024 - Springer
The transport of bicarbonate across the enterocyte cell membrane regulates the intracellular
as well as the luminal pH and is an essential part of directional fluid movement in the gut …

Balancing act of the intestinal antimicrobial proteins on gut microbiota and health

YE Ra, YJ Bang - Journal of Microbiology, 2024 - Springer
The human gut houses a diverse and dynamic microbiome critical for digestion, metabolism,
and immune development, exerting profound effects on human health. However, these …

Chemical genetic approaches to dissect microbiota mechanisms in health and disease

X Yang, HC Hang - Science, 2024 - science.org
Advances in genomics, proteomics, and metabolomics have revealed associations between
specific microbiota species in health and disease. However, the precise mechanism (s) of …

The hidden base of the iceberg: gut peptidoglycome dynamics is foundational to its influence on the host

R Wheeler, I Gomperts Boneca - Gut microbes, 2024 - Taylor & Francis
The intestinal microbiota of humans includes a highly diverse range of bacterial species. All
these bacteria possess a cell wall, composed primarily of the macromolecule peptidoglycan …

[HTML][HTML] Elevated muramyl dipeptide by sialic acid-facilitated postantibiotic pathobiont expansion contributes to gut dysbiosis-induced mastitis in mice

M Qiu, C Ye, L Bao, K Wu, Y Zhao, X Zhao… - Journal of Advanced …, 2024 - Elsevier
Introduction In responses to antibiotics exposure, gut dysbiosis is a risk factor not only for
pathogen infection but also for facilitating pathobiont expansion, resulting in increased …

[HTML][HTML] Industrial-produced lemon nanovesicles ameliorate experimental colitis-associated damages in rats via the activation of anti-inflammatory and antioxidant …

V Tinnirello, MG Zizzo, A Conigliaro, M Tabone… - Biomedicine & …, 2024 - Elsevier
Plant-derived nanovesicles (PDNVs) have recently emerged as natural delivery systems of
biofunctional compounds toward mammalian cells. Considering their already described …

The formidable guardian: Type 3 immunity in the intestine of pigs

Z Yang, D Zhang, Z Jiang, J Peng, H Wei - Virulence, 2024 - Taylor & Francis
Well-intestinal health is crucial for better growth performance in pigs. Type 3 immunity, which
is one of the three types of immune responses in mammals, plays a vital role in maintaining …