Pichia pastoris is an established protein expression host mainly applied for the production of
biopharmaceuticals and industrial enzymes. This methylotrophic yeast is a distinguished …

Besides its use for efficient production of recombinant proteins the methylotrophic yeast
Pichia pastoris (syn. Komagataella spp.) has been increasingly employed as a platform to …

During the past 15 years, the methylotrophic yeast Pichia pastoris has developed into a
highly successful system for the production of a variety of heterologous proteins. The …

Yeasts combine the ease of genetic manipulation and fermentation of a microorganism with
the capability to secrete and modify foreign proteins according to a general eukaryotic …

The methylotrophic yeast Pichia pastoris is an established protein expression host for the
production of industrial enzymes. This yeast can be grown to very high cell densities and …

Over the past 100 years, industrial biotechnology has grown into a multibillion dollar market,
which now has even begun to include large parts of chemical, material, and fuel production …

The yeast Pichia pastoris has become the premier example of yeast species used for the
production of recombinant proteins. Advantages of this yeast for expression include tightly …

Recombinant proteins are important tools for studying biological processes. Generating a
recombinant protein requires the use of an expression system. Selection of an appropriate …

Highlights•Genome editing technologies were adapted for gene disruption, deletion and
editing in P. pastoris.•New chassis strains for facilitated expression of complex …

It was observed that during fermentative production of recombinant ovine interferon‐τ (r‐
oIFN‐τ) in Pichia pastoris, a secreted recombinant protein, the protein was degraded …