Skin wounds greatly affect the global healthcare system, creating a substantial burden on
the economy and society. Moreover, the situation is exacerbated by low healing rates, which …

Chronic inflammation is one of the hallmarks of chronic wounds and is tightly coupled to
immune regulation. The dysregulation of the immune system leads to continuing …

Impaired wound healing in chronic wounds has been a significant challenge for clinicians
and researchers for decades. Traditional herbal medicine (THM) has a long history of …

Obesity is a major risk factor for psoriasis, but how obesity disrupts the regulatory
mechanisms that keep skin inflammation in check is unclear. Here, we found that skin was …

In acute skin injury, healing is impaired by the excessive release of reactive oxygen species
(ROS). Melanin, an efficient scavenger of radical species in the skin, performs a key role in …

Disorders in the regulatory arm of the adaptive immune system result in autoimmune‐
mediated diseases. While systemic immunosuppression is the prevailing approach to …

Psoriasis is a chronic inflammatory skin disease characterized by accelerated tumor
necrosis factor-α/interleukin (IL)-23/IL-17 axis. Patients with psoriasis manifest functional …

Allergic diseases are caused by a hypersensitivity reaction to an external substance that is
normally not harmful to the body. An imbalance between type 2 immune response and …

Atopic dermatitis (AD) is an inflammatory disorder centered around loss of epidermal barrier
function, and T helper 2 (Th2) immune responses. The current understanding of disease …

As the body's integumentary system, the skin is vulnerable to injuries. The subsequent
wound healing processes aim to restore dermal and epidermal integrity and functionality. To …