CMV infection and CMV-specific immune reconstitution following haploidentical stem cell transplantation: an update

XH Luo, Y Zhu, YT Chen, LP Shui, L Liu - Frontiers in Immunology, 2021 - frontiersin.org
Haploidentical stem cell transplantation (haploSCT) has advanced to a common procedure
for treating patients with hematological malignancies and immunodeficiency diseases …

The evolution of T cell depleted haploidentical transplantation

F Aversa, A Pierini, L Ruggeri, MF Martelli… - Frontiers in …, 2019 - frontiersin.org
Work on bone marrow transplantation from haploidentical donor has been proceeding for
over 20 years all over the world and new transplant procedures have been developed. To …

Results of a multicenter phase I/II trial of TCRαβ and CD19-depleted haploidentical hematopoietic stem cell transplantation for adult and pediatric patients

WA Bethge, M Eyrich, S Mielke, R Meisel… - Bone Marrow …, 2022 - nature.com
Hematopoietic stem cell transplantation (HSCT) from haploidentical donors is a viable
option for patients lacking HLA-matched donors. Here we report the results of a prospective …

Role of αβ T cell depletion in prevention of graft versus host disease

H Abdelhakim, H Abdel-Azim, A Saad - Biomedicines, 2017 - mdpi.com
Graft versus host disease (GVHD) represents a major complication of allogeneic
hematopoietic stem cell transplantation (allo HCT). Graft cellular manipulation has been …

Peripheral blood stem cell mobilization in healthy donors by granulocyte colony-stimulating factor causes preferential mobilization of lymphocyte subsets

GK Melve, E Ersvaer, GE Eide… - Frontiers in …, 2018 - frontiersin.org
Background Allogeneic hematopoietic stem cell transplantation is associated with a high risk
of immune-mediated post-transplant complications. Graft depletion of immunocompetent cell …

T-cell manipulation strategies to prevent graft-versus-host disease in haploidentical stem cell transplantation

J Vadakekolathu, S Rutella - Biomedicines, 2017 - mdpi.com
Allogeneic haematopoietic stem cell transplantation (HSCT) from an human leukocyte
antigen (HLA)-identical donor can be curative for eligible patients with non-malignant and …

T-Cell-Replete Versus ex vivo T-Cell-Depleted Haploidentical Haematopoietic Stem Cell Transplantation in Children With Acute Lymphoblastic Leukaemia and Other …

K Kleinschmidt, M Lv, A Yanir, J Palma, P Lang… - Frontiers in …, 2021 - frontiersin.org
Allogeneic haematopoietic stem cell transplantation (HSCT) represents a potentially curative
option for children with high-risk or refractory/relapsed leukaemias. Traditional donor …

The current landscape: Allogeneic hematopoietic stem cell transplant for acute lymphoblastic leukemia

S Prockop, F Wachter - Best Practice & Research Clinical Haematology, 2023 - Elsevier
One of the consistent features in development of hematopoietic stem cell transplant (HCT)
for Acute Lymphoblastic Leukemia (ALL) is the rapidity with which discoveries in the …

Hematopoietic stem cell transplant with HLA-mismatched grafts: impact of donor, source, conditioning, and graft versus host disease prophylaxis

L Metheny, M de Lima - Expert Review of Hematology, 2019 - Taylor & Francis
Introduction: Allogeneic hematopoietic cell transplantation is frequently used to treat
malignant and non-malignant conditions, and many patients lack a human leukocyte antigen …

Effective T‐cell replete haploidentical stem cell transplantation for pediatric patients with high‐risk hematologic disorders

S Tannumsaeung, U Anurathapan… - European Journal of …, 2023 - Wiley Online Library
Objectives Patients with high‐risk hematologic diseases require intensive modalities,
including high‐dose chemotherapy and allogeneic hematopoietic stem cell transplantation …