The development of novel synthetic strategies to form new chemical entities in a
stereoselective manner is an ongoing significant objective in organic and medicinal …

Chiral seven-membered ring systems such as seven-membered carbocycles and
heterocycles are widely found in natural products and pharmaceuticals. Therefore, the …

We designed bifunctional 4-pyrrolidinopyridines as powerful Lewis base catalysts. The
catalyst structure features a 4-hydroxy-2-(hydroxydiphenylmethyl) pyrrolidine-1-formyl group …

Dual catalysis is one of the most powerful strategies for the development of chemical
reactions in organic synthesis. This strategy can be divided into cooperative catalysis, relay …

Diverse functionalized dihydrobenzofuran spiro-indanedione-oxindole scaffolds were
conveniently synthesized by base-promoted cyclization reaction of Morita–Baylis–Hillman …

Developing diversity-oriented synthetic approaches for medium-sized rings is of great
interest, and the divergent synthesis of medium-sized rings with different ring sizes poses a …

An efficient synthetic protocol for the selective construction of spiro [indoline-3, 5′-pyrrolo
[3, 4-b] azepines] and spiro [indoline-3, 3′-pyrroles] via a cycloaddition reaction of α, β …

Catalytic asymmetric multicomponent 1, 2-boronate rearrangements provide a practical
approach for synthesizing highly valuable enantioenriched boronic esters. When applied to …

We have developed an efficient protocol for the construction of polycyclic dihydrobenzofuran
spirooxindole scaffolds via base promoted cascade annulation of Morita–Baylis–Hillman …

Organocatalytic asymmetric [3+ 3] annulations of isatin-derived MBH carbonates and indolin-
2-imines were efficiently achieved. This appears to be the first enantioselective approach for …